GEMIN5 Antikörper
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- Target Alle GEMIN5 Antikörper anzeigen
- GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GEMIN5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Immunogen
- gem (nuclear organelle) associated protein 5
- Isotyp
- IgG
- Top Product
- Discover our top product GEMIN5 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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Jurkat cells were subjected to SDS PAGE followed by western blot with FNab03420( GEMIN5 Antibody) at dilution of 1:1500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- GEMIN5 (Gem (Nuclear Organelle) Associated Protein 5 (GEMIN5))
- Andere Bezeichnung
- GEMIN5 (GEMIN5 Produkte)
- Synonyme
- GEMIN-5 antikoerper, AA407055 antikoerper, AA407208 antikoerper, AI451603 antikoerper, BB194447 antikoerper, C330013N08 antikoerper, gem nuclear organelle associated protein 5 antikoerper, gem (nuclear organelle) associated protein 5 antikoerper, GEMIN5 antikoerper, Gemin5 antikoerper
- Hintergrund
- Synonyms: Background:The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins(snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus. GEMIN5 acts as the snRNA-binding protein of the SMN complex.
- Molekulargewicht
- 168 kDa
- Gen-ID
- 25929
- UniProt
- Q8TEQ6
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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