CHST14 Antikörper

Produktnummer ABIN5703207

Produktdetails anti-CHST14 Antikörper

Target: CHST14 (Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 (CHST14))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHST14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab01694(CHST14 antibody) at dilution of 1:600

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu CHST14

Target: CHST14 (Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 (CHST14))

Andere Bezeichnung: CHST14 (CHST14 Produkte)

Synonyme: ATCS antikoerper, D4ST1 antikoerper, HNK1ST antikoerper, 2600016L03Rik antikoerper, D4ST-1 antikoerper, D4st1 antikoerper, d4st1 antikoerper, MGC136487 antikoerper, wu:fc04a01 antikoerper, zgc:136487 antikoerper, carbohydrate sulfotransferase 14 antikoerper, carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 antikoerper, CHST14 antikoerper, Chst14 antikoerper, chst14 antikoerper

Hintergrund: Synonyms:D4ST1 Background:Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine(GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid(IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in-IdoUA-GalNAc-IdoUA-than in-GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. GlcUA to IdoUA. Appears to have an important role in the formation of the cerbellar neural network during postnatal brain development.

Molekulargewicht: 45-50 kDa

Gen-ID: 113189

UniProt: Q8NCH0

Pathways: Glycosaminoglycan Metabolic Process