SUN1 Antikörper

Produktnummer ABIN5703165

Produktdetails anti-SUN1 Antikörper

Target: SUN1 (Sad1 and UNC84 Domain Containing 1 (SUN1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Immunogen: unc-84 homolog A (C. elegans)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB : 1:500-1:5000

Kommentare:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab08392( UNC84A Antibody) at dilution of 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.1 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu SUN1

Target: SUN1 (Sad1 and UNC84 Domain Containing 1 (SUN1))

Andere Bezeichnung: SUN1 (SUN1 Produkte)

Synonyme: UNC84A antikoerper, 4632417G13Rik antikoerper, 5730434D03Rik antikoerper, Unc84a antikoerper, mKIAA0810 antikoerper, Sun domain-containing protein 1 antikoerper, Sad1 and UNC84 domain containing 1 antikoerper, sun-1 antikoerper, SUN1 antikoerper, Sun1 antikoerper

Hintergrund: Synonyms:KIAA0810, UNC84A Background:Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration(INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes(NPCs)(By similarity). Required for efficient localization of SYNE4 in the nuclear envelope(By similarity).

Molekulargewicht: 90 kDa

Gen-ID: 23353

UniProt: O94901

Pathways: Maintenance of Protein Location