Histone Cluster 3, H3 (HIST3H3) Antikörper

Produktnummer ABIN5702948

Produktdetails

Target: Histone Cluster 3, H3 (HIST3H3)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogen: histone cluster 2, H3a

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB : 1:500-1:5000 IHC : 1:50-1:200 IF : 1:20-1:200

Kommentare:

MCF7 cells were subjected to SDS PAGE followed by western blot with FNab03890(Histone-H3 antibody) at dilution of 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Antigendetails

Target: Histone Cluster 3, H3 (HIST3H3)

Andere Bezeichnung: Histone-H3 (HIST3H3 Produkte)

Synonyme: H3.4 antikoerper, H3/g antikoerper, H3FT antikoerper, H3t antikoerper, H3/A antikoerper, H3FA antikoerper, H3.2-221 antikoerper, Hist1 antikoerper, histone cluster 3 H3 antikoerper, histone cluster 1 H3 family member a antikoerper, histone cluster 3, H3 antikoerper, histone cluster 1, H3f antikoerper, HIST3H3 antikoerper, HIST1H3A antikoerper, Hist1h3f antikoerper

Hintergrund: Synonyms:H3/n, H3/o, H3F2, H3FM, HIST2H3A, HIST2H3C, HIST2H3D, histone cluster 2, H3a, Histone H3, Histone H3.2, Histone H3/m, Histone H3/o Background:HIST2H3A,histone cluster 2, H3a.It is the core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. HIST2H3A is Expressed during S phase, then expression strongly decreases as cell division slows down during the process of differentiation.

Molekulargewicht: 15-17 kDa

UniProt: Q71DI3