GPR177/WLS Antikörper

Produktnummer ABIN5702909

Produktdetails anti-GPR177/WLS Antikörper

Target: GPR177/WLS (WLS) (Wntless Homolog (WLS))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR177/WLS Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Immunogen: G protein-coupled receptor 177

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab03601(GPR177 antibody) at dilution of 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu GPR177/WLS

Target: GPR177/WLS (WLS) (Wntless Homolog (WLS))

Andere Bezeichnung: GPR177 (WLS Produkte)

Synonyme: C1orf139 antikoerper, EVI antikoerper, GPR177 antikoerper, MRP antikoerper, mig-14 antikoerper, 5031439A09Rik antikoerper, AI173978 antikoerper, AI987742 antikoerper, Gpr177 antikoerper, gpr117 antikoerper, gpr177 antikoerper, sb:cb610 antikoerper, wu:fb36d04 antikoerper, wu:fb44d10 antikoerper, wu:fb50c06 antikoerper, zgc:64091 antikoerper, CG6210 antikoerper, Dmel\\CG6210 antikoerper, Evi antikoerper, Evi/Wls antikoerper, Srt antikoerper, Wls antikoerper, Wls/Evi antikoerper, evi antikoerper, srt antikoerper, wls/evi antikoerper, wntless Wnt ligand secretion mediator antikoerper, wntless homolog (Drosophila) antikoerper, wntless antikoerper, WLS antikoerper, Wls antikoerper, wls antikoerper

Hintergrund: Synonyms:C1orf139, EVI, G protein coupled receptor 177, GPR177, Protein wntless homolog, Sprinter, WLS, Wntless Background:GPR177, also known as Wntless (WLS) or Evi, is an evolutionarily conserved transmembrane protein necessary for Wnt protein secretion. GPR177 localizes to compartments of the secretory pathway, including the ER, Golgi apparatus, endosomes, and plasma membrane. GPR177 is overexpressed in several cancer types including glioma and gastric cancer. Several isoforms of GPR177 exist due to the alternative splicing, with predicted MW around 62 and 51 kDa, respectively. The sequence can be processed by removing the signal peptide, which generates a mature form of 45-46 kDa. In addition, slow migragrating band above 62 kDa can also be detected because GPR177 is modified by N-linked glycosylation (PMID: 20549736).

Molekulargewicht: 46-62 kDa

Pathways: WNT Signalweg