MLXIP Antikörper

Produktnummer ABIN5701831

Produktdetails anti-MLXIP Antikörper

Target: MLXIP (MLX Interacting Protein (MLXIP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MLXIP Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogen: MLX interacting protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

K-562 cells were subjected to SDS PAGE followed by western blot with FNab05223(MLXIP antibody) at dilution of 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu MLXIP

Target: MLXIP (MLX Interacting Protein (MLXIP))

Andere Bezeichnung: MLXIP (MLXIP Produkte)

Synonyme: MGC83884 antikoerper, si:ch211-110p13.4 antikoerper, MIR antikoerper, MONDOA antikoerper, bHLHe36 antikoerper, AW228700 antikoerper, B930074I24 antikoerper, Mir antikoerper, mKIAA0867 antikoerper, RGD1560774 antikoerper, MLX interacting protein antikoerper, MLX interacting protein L homeolog antikoerper, MLXIP antikoerper, mlxip.L antikoerper, mlxip antikoerper, Mlxip antikoerper

Hintergrund: Synonyms:BHLHE36, KIAA0867, MIR, MONDOA Background:Mlx-interacting protein(MLXIP), after forming heterodimers with MLX, can bind to and then activate transcription from CACGTG E boxes. The N terminus of MLXIP acts as a CRM1-dependent nuclear export signal and contribute to the cytoplasmic localization of the complex, and as a binding site for 13 protein. the C terminus contains a cytoplasmic localization signal and mediates protein-protein interaction of MONDOA and MLX. The complex play a role in transcriptional activation of glycolytic target genes and glucose-responsive gene regulation. This antibody could recognize isoform1(~110kd) and isoform3(~69kd) of MLXIP. A specific MLXIP of approximately 130 kDa was detected. It demonstrates that MLXIP associated specifically with Mlx in the cytoplasm (PMID: 11073985).

Molekulargewicht: 130 kDa

Gen-ID: 22877

UniProt: Q9HAP2