MACF1 Antikörper

Produktnummer ABIN5701487

Produktdetails anti-MACF1 Antikörper

Target: MACF1 (Microtubule-Actin Crosslinking Factor 1 (MACF1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MACF1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogen: microtubule-actin crosslinking factor 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu MACF1

Target: MACF1 (Microtubule-Actin Crosslinking Factor 1 (MACF1))

Andere Bezeichnung: MACF1 (MACF1 Produkte)

Synonyme: ABP620 antikoerper, ACF7 antikoerper, MACF antikoerper, OFC4 antikoerper, Acf7 antikoerper, Aclp7 antikoerper, R74989 antikoerper, mKIAA0465 antikoerper, MACF1 antikoerper, fc46g01 antikoerper, wu:fc46g01 antikoerper, si:rp71-45k5.7 antikoerper, acf7 antikoerper, macf antikoerper, ofc4 antikoerper, abp620 antikoerper, DKFZp469K2016 antikoerper, Kiaa0754 antikoerper, mKIAA0754 antikoerper, microtubule-actin crosslinking factor 1 antikoerper, microtubule-actin crosslinking factor 1a antikoerper, microtubule-actin cross-linking factor 1 antikoerper, dual specificity protein kinase CLK3 antikoerper, microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 antikoerper, KIAA0754 antikoerper, RIKEN cDNA D830031N03 gene antikoerper, MACF1 antikoerper, Macf1 antikoerper, macf1a antikoerper, macf1 antikoerper, LOC100175356 antikoerper, LOC100514848 antikoerper, LOC100550622 antikoerper, KIAA0754 antikoerper, D830031N03Rik antikoerper

Hintergrund: Synonyms:ABP620, ACF7, KIAA0465, KIAA1251 Background:Isoform 2 is a F-actin-binding protein which may play a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Acts as a positive regulator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex(composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane. Has actin-regulated ATPase activity and is essential for controlling focal adhesions(FAs) assembly and dynamics. May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with GOLGA4. Plays a key role in wound healing and epidermal cell migration. Required for efficient upward migration of bulge cells in response to wounding and this function is primarily rooted in its ability to coordinate MT dynamics and polarize hair follicle stem cells(By similarity).

Gen-ID: 23499

UniProt: Q9UPN3