MAP3K3 Antikörper

Produktnummer ABIN5701066

Produktdetails anti-MAP3K3 Antikörper

Target: MAP3K3 (Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP3K3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: mitogen-activated protein kinase kinase kinase 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB : 1:200-1:1000 IHC : 1:50-1:500

Kommentare:

mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab09784( MAP3K3 Antibody) at dilution of 1:300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Handhabung: Avoid repeated freeze / thaw cycles.

Details zu MAP3K3

Target: MAP3K3 (Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3))

Andere Bezeichnung: MAP3K3 (MAP3K3 Produkte)

Synonyme: MAPKKK3 antikoerper, MEKK3 antikoerper, AW548911 antikoerper, Mekk3 antikoerper, mKIAA4031 antikoerper, mitogen activated protein kinase kinase kinase 3 antikoerper, mitogen-activated protein kinase kinase kinase 3 antikoerper, Map3k3 antikoerper, MAP3K3 antikoerper, map3k3 antikoerper

Hintergrund: Synonyms:MAP3K3, MAPK/ERK kinase kinase 3, MAPKKK3, MEK kinase 3, MEKK 3, MEKK3 Background:The mitogen-activated protein/ERK kinase kinase 3(MEKK3) is a member of a family of MEKK/Ste11 serine/threonine protein kinases. One function of MEKK3 is to serve as an upstream regulatory kinase in the mitogen-activated protein kinase cascade, however, it also plays a critical role in other signaling pathways. MEKK3 regulates several important functions including cell survival and proliferation. It is ubiquitously expressed in multiple tissues and has been found in complexes with scaffold proteins and other kinases.(PMID: 18206350).Cerebral cavernous malformations(CCMs) complex regulation of MEKK3 is essential during vertebrate heart development. MEKK3 signalling and KLF2/4 may be targeted to develop new CCM therapeutics.

Molekulargewicht: 36kDa

UniProt: Q99759

Pathways: MAPK Signalweg