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DNAJC10 Antikörper

DNAJC10 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5700761
  • Target Alle DNAJC10 Antikörper anzeigen
    DNAJC10 (DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10))
    Reaktivität
    • 27
    • 19
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 35
    • 4
    Kaninchen
    Klonalität
    • 36
    • 3
    Polyklonal
    Konjugat
    • 15
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DNAJC10 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 20
    • 13
    • 13
    • 4
    • 3
    • 3
    • 3
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Immunogen
    DnaJ (Hsp40) homolog, subfamily C, member 10
    Isotyp
    IgG
    Top Product
    Discover our top product DNAJC10 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Kommentare

    HeLa cells were subjected to SDS PAGE followed by western blot with FNab02457(DNAJC10 antibody) at dilution of 1:1500

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze / thaw cycles.
    Lagerung
    -20 °C
    Haltbarkeit
    12 months
  • Target
    DNAJC10 (DnaJ (Hsp40) Homolog, Subfamily C, Member 10 (DNAJC10))
    Andere Bezeichnung
    DNAJC10 (DNAJC10 Produkte)
    Synonyme
    ERdj5 antikoerper, JPDI antikoerper, MTHr antikoerper, PDIA19 antikoerper, 1200006L06Rik antikoerper, D2Ertd706e antikoerper, dnajc10 antikoerper, zgc:162218 antikoerper, DnaJ heat shock protein family (Hsp40) member C10 antikoerper, DnaJ (Hsp40) homolog, subfamily C, member 10 antikoerper, DNAJC10 antikoerper, Dnajc10 antikoerper, dnajc10 antikoerper
    Hintergrund
    Synonyms:ERDJ5 Background:Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation(ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress.
    Molekulargewicht
    75-80 kDa
    Gen-ID
    54431
    UniProt
    Q8IXB1
    Pathways
    Cell RedoxHomeostasis
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