GSDMD Antikörper

Produktnummer ABIN5699829

Produktdetails anti-GSDMD Antikörper

Target: GSDMD (Gasdermin D (GSDMD))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSDMD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogen: gasdermin D

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB : 1:200-1:2000 IHC : 1:20-1:200 IF : 1:10-1:100

Kommentare:

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab03670( GSDMD Antibody) at dilution of 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu GSDMD

Target: GSDMD (Gasdermin D (GSDMD))

Andere Bezeichnung: GSDMD (GSDMD Produkte)

Synonyme: GSDMDC1 antikoerper, GSDMD antikoerper, DF5L antikoerper, DFNA5L antikoerper, 1810036L03Rik antikoerper, AW558049 antikoerper, Dfna5l antikoerper, Gsdmdc1 antikoerper, M2-4 antikoerper, gasdermin D antikoerper, GSDMD antikoerper, Gsdmd antikoerper

Hintergrund: Synonyms:DF5L, DFNA5L, FKSG10, FLJ12150, gasdermin D, GSDMD, GSDMDC1 Background:GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.

Molekulargewicht: 50-53 kDa

Gen-ID: 79792

UniProt: P57764

Pathways: Inflammasome