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GNAI1 Antikörper

GNAI1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5699458
  • Target Alle GNAI1 Antikörper anzeigen
    GNAI1 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1))
    Reaktivität
    • 29
    • 9
    • 9
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 25
    • 4
    Kaninchen
    Klonalität
    • 26
    • 3
    Polyklonal
    Konjugat
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GNAI1 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 13
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
    Immunogen
    guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
    Isotyp
    IgG
    Top Product
    Discover our top product GNAI1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Kommentare

    human brain tissue were subjected to SDS PAGE followed by western blot with FNab03531(GNAI1 antibody) at dilution of 1:1600

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze / thaw cycles.
    Lagerung
    -20 °C
    Haltbarkeit
    12 months
  • Target
    GNAI1 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1))
    Andere Bezeichnung
    GNAI1 (GNAI1 Produkte)
    Synonyme
    AU046200 antikoerper, Gialpha1 antikoerper, Gnai-1 antikoerper, gnai1 antikoerper, Gi antikoerper, BPGTPB antikoerper, zgc:63957 antikoerper, guanine nucleotide binding protein (G protein), alpha inhibiting 1 antikoerper, G protein subunit alpha i1 antikoerper, guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 S homeolog antikoerper, guanine nucleotide-binding protein G(i) subunit alpha-1 antikoerper, guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 antikoerper, Gnai1 antikoerper, gnai1.S antikoerper, GNAI1 antikoerper, LOC397505 antikoerper, gnai1 antikoerper
    Hintergrund
    Synonyms: Background:Guanine nucleotide-binding proteins(G proteins) function as transducers downstream of G protein-coupled receptors(GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins(PubMed:8774883, PubMed:18434541). Signaling is mediated via effector proteins, such as adenylate cyclase. Inhibits adenylate cyclase activity, leading to decreased intracellular cAMP levels(By similarity). The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. Required for normal cytokinesis during mitosis(PubMed:17635935).
    Molekulargewicht
    40 kDa
    Gen-ID
    2770
    UniProt
    P63096
    Pathways
    G-protein mediated Events
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