Sphingomyelin Synthase 1 Antikörper

Produktnummer ABIN5698483

Produktdetails anti-Sphingomyelin Synthase 1 Antikörper

Target: Sphingomyelin Synthase 1 (SGMS1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Sphingomyelin Synthase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: sphingomyelin synthase 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

human heart tissue were subjected to SDS PAGE followed by western blot with FNab07811(SGMS1 antibody) at dilution of 1:300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu Sphingomyelin Synthase 1

Target: Sphingomyelin Synthase 1 (SGMS1)

Andere Bezeichnung: SGMS1 (SGMS1 Produkte)

Synonyme: MGC81436 antikoerper, TMEM23 antikoerper, MOB antikoerper, MOB1 antikoerper, SMS1 antikoerper, hmob33 antikoerper, 9530058O11Rik antikoerper, AI841905 antikoerper, C80702 antikoerper, Mob antikoerper, Sms1 antikoerper, Sor1 antikoerper, Tmem23 antikoerper, sphingomyelin synthase 1 antikoerper, sphingomyelin synthase 1 S homeolog antikoerper, phosphatidylcholine:ceramide cholinephosphotransferase 1 antikoerper, SGMS1 antikoerper, sgms1.S antikoerper, LOC100013212 antikoerper, Sgms1 antikoerper

Hintergrund: Synonyms:MOB, SMS1, TMEM23 Background:Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.

Gen-ID: 259230

UniProt: Q86VZ5

Pathways: Cellular Response to Molecule of Bacterial Origin