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HTRA1 Antikörper

HTRA1 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5692999
  • Target Alle HTRA1 Antikörper anzeigen
    HTRA1 (HtrA Serine Peptidase 1 (HTRA1))
    Reaktivität
    • 59
    • 15
    • 11
    • 2
    • 2
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 61
    • 1
    Kaninchen
    Klonalität
    • 62
    Polyklonal
    Konjugat
    • 24
    • 8
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser HTRA1 Antikörper ist unkonjugiert
    Applikation
    • 45
    • 35
    • 26
    • 13
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    QLRAASRRSE RLHRPPVIVL QRGACGQGQE DPNSLRHKYN FIAD
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for HTRA1 detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Immunogen
    A synthetic peptide corresponding to a sequence of human HTRA1 (QLRAASRRSERLHRPPVIVLQRGACGQGQEDPNSLRHKYNFIAD).
    Top Product
    Discover our top product HTRA1 Primärantikörper
  • Applikationshinweise

    Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    Application Details: Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry(Paraffin-embedded Section), 0.5-1 μg/mL

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • Target
    HTRA1 (HtrA Serine Peptidase 1 (HTRA1))
    Andere Bezeichnung
    HTRA1 (HTRA1 Produkte)
    Synonyme
    htra1 antikoerper, zgc:92029 antikoerper, zgc:172061 antikoerper, l56 antikoerper, htra antikoerper, Xhtra1 antikoerper, prss11 antikoerper, MGC145723 antikoerper, ARMD7 antikoerper, CARASIL antikoerper, HtrA antikoerper, L56 antikoerper, ORF480 antikoerper, PRSS11 antikoerper, AI429470 antikoerper, HTRA antikoerper, Prss11 antikoerper, RSPP11 antikoerper, HTRA1 antikoerper, HtrA serine peptidase 1a antikoerper, HtrA serine peptidase 1 antikoerper, HtrA serine peptidase 1b antikoerper, Serine protease HTRA1 antikoerper, HtrA serine peptidase 1 S homeolog antikoerper, htra1a antikoerper, HTRA1 antikoerper, htra1b antikoerper, htra1 antikoerper, Htra1 antikoerper, htra1.S antikoerper
    Hintergrund

    Synonyms: Serine protease HTRA1, High-temperature requirement A serine peptidase 1, L56, Serine protease 11, HTRA1, HTRA, PRSS11

    Tissue Specificity: Widely expressed, with strongest expression in placenta (at protein level). Secreted by synovial fibroblasts. Up- regulated in osteoarthritis and rheumatoid arthritis synovial fluids and cartilage as compared with non-arthritic (at protein level).

    Background: Serine protease HTRA1 is an enzyme that in humans is encoded by the HTRA1 gene. This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7.

    UniProt
    Q92743
    Pathways
    Growth Factor Binding
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