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SOGA1 Antikörper (C-Term)
SOGA1
Reaktivität: Human
WB, ELISA, IF
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5690262
Produktdetails anti-SOGA1 Antikörper
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Target
Alle SOGA1 Antikörper anzeigen
SOGA1
(Suppressor of Glucose, Autophagy Associated 1 (SOGA1))
Bindungsspezifität
Alle Epitope für SOGA1 Antikörper
C-Term
Reaktivität
Alle Reaktivitäten für SOGA1 Antikörper
Human
Wirt
Alle Wirte für SOGA1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für SOGA1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für SOGA1 Antikörper
Dieser SOGA1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für SOGA1 Antikörper
Western Blotting (WB), ELISA, Immunofluorescence (IF)
Spezifität
SOGA1 antibody is human specific. At least four isoforms of SOGA1 are known to exist.
Aufreinigung
SOGA1 Antibody is affinity chromatography purified via peptide column.
Immunogen
SOGA1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human SOGA. The immunogen is located within the last 50 amino acids of SOGA1 .
Isotyp
IgG
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Anwendungsinformationen
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Applikationshinweise
SOGA1 antibody can be used for detection of SOGA1 by Western blot at 1 - 2 μ,g/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
SOGA1 Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
SOGA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Details zu SOGA1
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Target
SOGA1
(Suppressor of Glucose, Autophagy Associated 1 (SOGA1))
Andere Bezeichnung
SOGA1 (SOGA1 Produkte )
Synonyme
C20orf117 antikoerper, KIAA0889 antikoerper, SOGA antikoerper, suppressor of glucose, autophagy associated 1 antikoerper, SOGA1 antikoerper
Hintergrund
The recently identified protein suppressor of glucose by autophagy protein 1 (SOGA1) has been found to be involved in the regulation of autophagy (1). SOGA1 is thought to contribute to adiponectin-mediated insulin-dependent inhibition of autophagy during the activation of adenosine monophosphate kinase (AMPK) (1,2). SOGA1 contains an internal signal peptide that enables the secretion of a circulating fragment of SOGA1, providing a surrogate marker for intracellular SOGA1 levels (2). Knockdown of SOGA1 elevated glucose production in primary hepatocytes indicates that SOGA1 is an inhibitor of glucose production. It thus might be useful as a novel therapeutic target for diabetes (3).
Molekulargewicht
Predicted: 183 kDa Observed: 200kDa
Gen-ID
140710
NCBI Accession
NP_954650
UniProt
O94964
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