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P2RX7 Antikörper (C-Term)

P2RX7 Reaktivität: Human, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5690089
  • Target Alle P2RX7 Antikörper anzeigen
    P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
    Bindungsspezifität
    • 15
    • 11
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 58
    • 40
    • 19
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Maus
    Wirt
    • 57
    • 2
    • 2
    • 1
    Kaninchen
    Klonalität
    • 58
    • 4
    Polyklonal
    Konjugat
    • 28
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser P2RX7 Antikörper ist unkonjugiert
    Applikation
    • 48
    • 26
    • 23
    • 13
    • 13
    • 12
    • 10
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    P2RX7 antibody is human, mouse, and rat reactive. Multiple isoforms of P2RX7 are known to exist.
    Aufreinigung
    P2RX7 antibody is affinity chromatography purified via peptide column.
    Immunogen
    P2RX7 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human P2RX7.

    The immunogen is located within the last 50 amino acids of P2RX7.
    Isotyp
    IgG
    Top Product
    Discover our top product P2RX7 Primärantikörper
  • Applikationshinweise
    P2RX7 antibody can be used for detection of P2RX7 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    P2RX7 antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    P2RX7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Target
    P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
    Andere Bezeichnung
    P2RX7 (P2RX7 Produkte)
    Synonyme
    p2xr7 antikoerper, P2RX7 antikoerper, P2X7 antikoerper, AI467586 antikoerper, P2X(7) antikoerper, P2X7R antikoerper, p2x7 antikoerper, purinergic receptor P2X 7 antikoerper, purinergic receptor P2X, ligand-gated ion channel, 7 antikoerper, P2X purinoceptor 7 antikoerper, P2RX7 antikoerper, p2rx7 antikoerper, LOC100458463 antikoerper, P2rx7 antikoerper
    Hintergrund
    The purinergic receptor P2X ligand-gated ion channel 7 (P2RX7) belongs to the family of purinoceptors for ATP (1). This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules (1,2). Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression (2). Recent studies have suggested that P2RX7 may play a key role in immune-mediated diseases such as rheumatoid arthritis (3) as well as neuropsychiatric disorders (4).
    Molekulargewicht
    Predicted: 34, 47, 65 kDa

    Observed: 54 kDa
    Gen-ID
    5027
    NCBI Accession
    NP_002553
    UniProt
    Q99572
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
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