Tamalin/GRASP Antikörper (AA 814-818)
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- Target Alle Tamalin/GRASP (GRASP) Antikörper anzeigen
- Tamalin/GRASP (GRASP) (GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP))
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Bindungsspezifität
- AA 814-818
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Reaktivität
- Maus, Ratte, Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Tamalin/GRASP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- This antibody detects endogenous level of total GRASP protein.
- Aufreinigung
- Antibodies were purified by affinity-chromatography using epitope-specific peptide
- Immunogen
- GRASP antibody was raised against a peptide sequence around aa. 814-818 (Q-E-I-V-R ) derived from Rat GRASP.
- Top Product
- Discover our top product GRASP Primärantikörper
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- Applikationshinweise
- Western Blot: 1:500~1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store antibody at -20°C for up to one year.
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- Target
- Tamalin/GRASP (GRASP) (GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP))
- Andere Bezeichnung
- GRASP (GRASP Produkte)
- Hintergrund
- GRASP (GRP1-associated scaffold protein, tamalin) is a 395 amino acid proteinencoded by the human gene GRASP . GRASP is a scaffold protein that com-prises multiple protein-interacting domains, including a 95 kDa postsynapticdensity protein (PSD-95)/discs-large/ZO-1 (PDZ) domain, a leucine-zipperregion and a carboxyl-terminal PDZ-binding motif. GRASP is involved withintracellular trafficking and contributes to the macromolecular organizationof group 1 metabotropic glutamate receptors (mGluRs) at synapses. GRASPforms a heteromer composed of GRASP , PSCD2 and at least one mGluR-1. Italso interacts with PSCD3, mGluR-2, mGluR-3 and mGluR-5. GRASP is highlyexpressed in brain and has lower levels of expression in lung, heart, embryo, kidney and ovary.
- Molekulargewicht
- 95 kDa
- Gen-ID
- 56850
- NCBI Accession
- NP_064522
- UniProt
- Q9JHZ4
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