Rekombinanter CD4 Antikörper
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- Target Alle CD4 Antikörper anzeigen
- CD4
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human, Rhesusaffen, Cynomolgus
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Wirt
- Kaninchen
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Klonalität
- Chimeric
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Konjugat
- Dieser CD4 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- Mt310 binds to the extracellular domain D1 of CD4 - the same site as the HIV-1 gp120-binding site
- Kreuzreaktivität
- Cynomolgus, Rhesusaffen
- Produktmerkmale
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OriginalSpeciesName: Mouse
OriginalFormat: IgG1
- Aufreinigung
- Purified antibody.
- Klon
- MT310
- Isotyp
- IgG kappa
- Top Product
- Discover our top product CD4 Primärantikörper
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anti-CD4 (CD4) (AA 385-457) antibody
CD4 Reaktivität: Human, Maus, Ratte, Huhn, Schwein FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD4 (CD4) antibodyCD4 Reaktivität: Human, Maus, Ratte, Huhn, Affe, Schwein, Hund, Cat, Kaninchen, Rind (Kuh), Schaf, Meerschweinchen, Ziege, Pferd, Avian, Esel, Hamster WB Wirt: Ziege Polyclonal unconjugated
anti-CD4 (CD4) (AA 231-330) antibodyCD4 Reaktivität: Human, Maus, Ratte FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD4 (CD4) (N-Term) antibodyCD4 Reaktivität: Human FACS, WB, CyTOF Wirt: Maus Monoclonal MEM-241 unconjugated
anti-CD4 (CD4) (AA 300-400) antibodyCD4 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-CD4 (CD4) antibodyCD4 Reaktivität: Maus FACS, IP, IHC (fro), ICC, Func Wirt: Ratte Monoclonal GK1-5 unconjugated
anti-CD4 (CD4) (N-Term) antibody (FITC)CD4 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-241 FITC
anti-CD4 (CD4) (AA 301-400) antibodyCD4 Reaktivität: Human, Maus, Ratte FACS, WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD4 (CD4) (N-Term) antibody (PE)CD4 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-241 PE
anti-CD4 (CD4) antibody (PE)CD4 Reaktivität: Ratte FACS Wirt: Maus Monoclonal OX-35 PE
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- Applikationshinweise
- mt310 can inhibit gp120 binding to CD4, which blocks HIV infectivity of CD4+ T lymphocytes, as well as the binding of MHCII, which results in the block of T-cell activation, possibly leading to the induction of anergy. Antibody binding to CD4 additionally causes the induction of GM-CSF, TNF-a (only after 20?h) and IL-10.
- Kommentare
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This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % Proclin 300.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Target
- CD4
- Andere Bezeichnung
- CD4 (CD4 Produkte)
- Synonyme
- cd4 antikoerper, L3T4 antikoerper, Ly-4 antikoerper, CD4mut antikoerper, W3/25 antikoerper, p55 antikoerper, CD4 molecule antikoerper, carcinoembryonic antigen-related cell adhesion molecule 5 antikoerper, T-cell surface glycoprotein CD4 antikoerper, CD4 antigen antikoerper, Cd4 molecule antikoerper, CD4 antikoerper, LOC100125525 antikoerper, cd4 antikoerper, Cd4 antikoerper
- Hintergrund
- Leu3/T3, T-cell differentiation antigen, Ly-4, L3T4, T-cell surface antigen T4/Leu-3
- UniProt
- P01730
- Pathways
- T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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