Rekombinanter CD33 (Gemtuzumab Biosimilar) Antikörper
Reaktivität: Human
FACS, IF
Wirt: Kaninchen
Monoclonal
HP67-6
unconjugated
Recombinant Antibody
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- Target Alle CD33 (Gemtuzumab Biosimilar) Produkte
- CD33 (Gemtuzumab Biosimilar)
- Antikörpertyp
- Recombinant Antibody
- Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD33 (Gemtuzumab Biosimilar) Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF)
- Spezifität
- Recognises human CD33.
- Produktmerkmale
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OriginalSpeciesName: Human
OriginalFormat: IgG4
- Aufreinigung
- Purified antibody.
- Reinheit
- > 98 % as determined by SDS-PAGE
- Endotoxin-Niveau
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
- Immunogen
- Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. CD33 is a transmembrane receptor expressed on predominantly on cells of the myeloid lineage, but it can also be found on some lymphoid cells.
- Klon
- HP67-6
- Isotyp
- IgG kappa
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- Applikationshinweise
- A human IgG4 variant conjugated to derivative of the cytotoxic drug calicheamicin gamma 1, N-acetylcalicheamicin dimethyl hydrazide, has been used as a therapeutic against acute myeloid leukemia. This antibody may also be used in flow cytometry and immunofluorescence.
- Kommentare
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This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % Proclin 300.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Target
- CD33 (Gemtuzumab Biosimilar)
- Abstract
- CD33 (Gemtuzumab Biosimilar) Produkte
- Synonyme
- SIGLEC-3 antikoerper, SIGLEC3 antikoerper, p67 antikoerper, CD33 molecule antikoerper, CD33 antikoerper
- Substanzklasse
- Biosimilar
- Hintergrund
- Siglec-3
- UniProt
- P20138
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