TRIB2 Antikörper (AA 254-343)

Produktnummer ABIN565396

Produktdetails anti-TRIB2 Antikörper

Target: TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

Bindungsspezifität: AA 254-343

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TRIB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)

Verwendungszweck: Mouse monoclonal antibody raised against a partial recombinant TRIB2.

Sequenz: FHDIEPSSLF SKIRRGQFNI PETLSPKAKC LIRSILRREP SERLTSQEIL DHPWFSTDFS VSNSAYGAKE VSDQLVPDVN MEENLDPFFN

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: TRIB2 (NP_067675, 254 a.a. ~ 343 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 1B1

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-TRIB2 Antikörper (ABIN565396)

Xu, Tong, Huang, Zhang, Qiao, Weng, Liu, Wang, Sun: "TRIB2 inhibits Wnt/?-Catenin/TCF4 signaling through its associated ubiquitin E3 ligases, ?-TrCP, COP1 and Smurf1, in liver cancer cells." in: FEBS letters, Vol. 588, Issue 23, pp. 4334-41, (2014) (PubMed).

Wang, Zhang, Weng, Qiao, Ma, Xiao, Yu, Pan, Sun et al.: "Impaired phosphorylation and ubiquitination by p70 S6 kinase (p70S6K) and Smad ubiquitination regulatory factor 1 (Smurf1) promote tribbles homolog 2 (TRIB2) stability and carcinogenic property in ..." in: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 33667-81, (2013) (PubMed).

Qiao, Zhang, Wang: "Ubiquitin E3 ligase SCF(?-TRCP) regulates TRIB2 stability in liver cancer cells." in: Biochemical and biophysical research communications, Vol. 441, Issue 3, pp. 555-9, (2013) (PubMed).

Details zu TRIB2

Target: TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

Andere Bezeichnung: TRIB2 (TRIB2 Produkte)

Synonyme: TRIB2 antikoerper, Trb2 antikoerper, Xtrbl antikoerper, gs3955 antikoerper, c5fw antikoerper, trb2 antikoerper, xtrb2 antikoerper, TRB2 antikoerper, C5FW antikoerper, GS3955 antikoerper, TRB-2 antikoerper, AW319517 antikoerper, RGD1564451 antikoerper, tribbles pseudokinase 2 antikoerper, tribbles pseudokinase 2 S homeolog antikoerper, TRIB2 antikoerper, trib2 antikoerper, trib2.S antikoerper, Trib2 antikoerper

Hintergrund: Full Gene Name: tribbles homolog 2 (Drosophila)
Synonyms: C5FW,GS3955,TRB2

Gen-ID: 28951

NCBI Accession: NM_021643