NFATC1 Antikörper (AA 110-210) (Alkaline Phosphatase (AP))
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- Target Alle NFATC1 Antikörper anzeigen
- NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
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Bindungsspezifität
- AA 110-210
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NFATC1 Antikörper ist konjugiert mit Alkaline Phosphatase (AP)
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Spezifität
- Expressed in thymus, peripheral leukocytes as T-cells and spleen. Isoforms A are preferentially expressed in effector T-cells (thymus and peripheral leukocytes) whereas isoforms B and isoforms C are preferentially expressed in naive T-cells (spleen). Isoforms B are expressed in naive T-cells after first antigen exposure and isoforms A are expressed in effector T-cells after second antigen exposure. Isoforms IA are widely expressed but not detected in liver nor pancreas, neural expression is strongest in corpus callosum. Isoforms IB are expressed mostly in muscle, cerebellum, placenta and thymus, neural expression in fetal and adult brain, strongest in corpus callosum.,Detects 90 kDa, band at ~60 kDa is another isoform.
- Kreuzreaktivität
- Human, Ratte
- Aufreinigung
- Peptide Affinity Purified
- Immunogen
- Synthetic peptide of Human NFATC1 (110-210 aa), conjugated to Keyhole Limpet Haemocyanin (KLH).
- Top Product
- Discover our top product NFATC1 Primärantikörper
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- Applikationshinweise
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- WB (1:1000)
- IHC (1:50)
- optimal dilutions for assays should be determined by the user.
- Kommentare
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A 1:1000 dilution of ABIN5651054 was sufficient for detection of NFATC1 in 15 μg of rat brain cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Conjugated antibodies should be stored at 4°C
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- Target
- NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))
- Andere Bezeichnung
- NFATC1 (NFATC1 Produkte)
- Synonyme
- nf-atc antikoerper, nfat2 antikoerper, nfatc antikoerper, si:ch211-198c22.2 antikoerper, NFATC1 antikoerper, 2210017P03Rik antikoerper, AI449492 antikoerper, AV076380 antikoerper, NF-ATc antikoerper, NFAT2 antikoerper, NFATc antikoerper, Nfatcb antikoerper, NF-ATC antikoerper, NF-ATc1 antikoerper, NFAT antikoerper, NFATmac antikoerper, nuclear factor of activated T-cells 1 antikoerper, nuclear factor of activated T-cells 1 L homeolog antikoerper, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 antikoerper, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 antikoerper, NFATC1 antikoerper, nfatc1.L antikoerper, nfatc1 antikoerper, Nfatc1 antikoerper
- Gen-ID
- 4772
- NCBI Accession
- NP_001265598
- UniProt
- O95644
- Pathways
- RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung
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