SIRT1 Antikörper (Sirtuin 1) (AA 456-555)

Details for Product anti-SIRT1 Antibody No. ABIN565071, Anbieter: Anmelden zum Anzeigen
Antigen
  • sirtuin 1
  • AA673258
  • SIR2L1
  • Sir2
  • Sir2a
  • Sir2alpha
  • sir2l1
  • sirtuin
  • SIR2
  • sirtuin 1
  • sirtuin 1 L homeolog
  • SIRT1
  • SRT1
  • Sirt1
  • sirt1.L
Epitop
AA 456-555, partial
27
26
20
15
15
11
11
10
10
7
6
6
5
5
4
3
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
319
156
71
21
12
11
7
7
7
6
5
4
4
2
2
2
2
1
Wirt
Maus
226
82
30
5
3
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser SIRT1 Antikörper ist unkonjugiert
18
15
9
7
7
5
5
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
273
146
108
67
62
46
43
41
40
14
6
4
4
2
2
2
2
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen SIRT1 (AAH12499, 456 a.a. ~ 555 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence: NRYIFHGAEV YSDSEDDVLS SSSCGSNSDS GTCQSPSLEE PMEDESEIEE FYNGLEDEPD VPERAGGAGF GTDGDDQEAI NEAISVKQEV TDMNYPSNKS
Klon 7B7
Isotyp IgG1 kappa
Kreuzreaktivität Human
Plasmids, Primers & others Plasmide, Primers & weitere SIRT1 products on genomics-online (e.g. as negative or positive controls)
Antigen Sirtuin 1 (SIRT1)
Andere Bezeichnung SIRT1 (SIRT1 Antibody Abstract)
Hintergrund Full Gene Name: sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)
Synonyms: SIR2L1
Gen-ID 23411
Pathways MAPK Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
Applikations-hinweise Optimal working dilution should be determined by the investigator.
Kommentare

Product Quality tested by: Antibody Reactive Against Recombinant Protein.

Beschränkungen Nur für Forschungszwecke einsetzbar
Buffer In 1x PBS, pH 7.4
Handhabung Aliquot to avoid repeated freezing and thawing.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Bilder des Herstellers
Western Blotting (WB) image for anti-Sirtuin 1 (SIRT1) (AA 456-555), (partial) antibody (ABIN565071) SIRT1 monoclonal antibody (M01), clone 7B7 Western Blot analysis of SIRT1 expression ...
Immunofluorescence (IF) image for anti-Sirtuin 1 (SIRT1) (AA 456-555), (partial) antibody (ABIN565071) Immunofluorescence of monoclonal antibody to SIRT1 on HeLa cell. [antibody concentrat...
Immunostaining (ISt) image for anti-Sirtuin 1 (SIRT1) (AA 456-555), (partial) antibody (ABIN565071) Immunoperoxidase of monoclonal antibody to SIRT1 on formalin-fixed paraffin-embedded ...
ELISA image for anti-Sirtuin 1 (SIRT1) (AA 456-555), (partial) antibody (ABIN565071) Detection limit for recombinant GST tagged SIRT1 is approximately 0.1ng/ml as a captu...
 image for anti-Sirtuin 1 (SIRT1) (AA 456-555), (partial) antibody (ABIN565071) Western Blot detection against Immunogen (36.63 KDa) .
Produkt verwendet in: Kok, Lin, Hou, Hong, Chang, Hsiao, Wang, Lai, Lin: "Simvastatin inhibits cysteine-rich protein 61 expression in rheumatoid arthritis synovial fibroblasts through the regulation of sirtuin-1/FoxO3a signaling." in: Arthritis and rheumatism, Vol. 65, Issue 3, pp. 639-49, 2013 (PubMed).

Østrup, Hyttel, Klærke, Collas: "Remodeling of ribosomal genes in somatic cells by Xenopus egg extract." in: Biochemical and biophysical research communications, Vol. 412, Issue 3, pp. 487-93, 2011 (PubMed).

Hiraike, Wada-Hiraike, Nakagawa, Koyama, Miyamoto, Sone, Tanikawa, Tsuruga, Nagasaka, Matsumoto, Oda, Shoji, Fukuhara, Saji, Nakagawa, Kato, Yano, Taketani: "Identification of DBC1 as a transcriptional repressor for BRCA1." in: British journal of cancer, Vol. 102, Issue 6, pp. 1061-7, 2010 (PubMed).

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