LILRA3 Antikörper (AA 1-439)

Produktnummer ABIN564777

Produktdetails anti-LILRA3 Antikörper

Target: LILRA3 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3))

Bindungsspezifität: AA 1-439

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LILRA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: Mouse monoclonal antibody raised against a full length recombinant LILRA3.

Sequenz: MTSILTVLIC LGLSLDPRTH VQAGPLPKPT LWAEPGSVIT QGSPVTLRCQ GSLETQEYHL YREKKTALWI TRIPQELVKK GQFPILSITW EHAGRYCCIY GSHTVGLSES SDPLELVVTG AYSKPTLSAL PSPVVTSGGN VTIQCDSQVA FDGFILCKEG EDEHPQCLNS HSHARGSSRA IFSVGPVSPS RRWSYRCYGY DSRAPYVWSL PSDLLGLLVP GVSKKPSLSV QPGPVVAPGE KLTFQCGSDA GYDRFVLYKE WGRDFLQRPG RQPQAGLSQA NFTLGPVSRS YGGQYTCSGA YNLSSEWSAP SDPLDILITG QIRARPFLSV RPGPTVASGE NVTLLCQSQG GMHTFLLTKE GAADSPLRLK SKRQSHKYQA EFPMSPVTSA HAGTYRCYGS LSSNPYLLTH PSDPLELVVS GAAETLSPPQ NKSDSKAGE

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: LILRA3 (AAH28208.1, 1 a.a. ~ 439 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 2E9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-LILRA3 Antikörper (ABIN564777)

An, Brettle, Lee, Heng, Lim, Guillemin, Lord, Klotzsch, Geczy, Bryant, Fath, Tedla: "Soluble LILRA3 promotes neurite outgrowth and synapses formation through a high-affinity interaction with Nogo 66." in: Journal of cell science, Vol. 129, Issue 6, pp. 1198-209, (2016) (PubMed).

An, Lim, Guillemin, Vollmer-Conna, Rawlinson, Bryant, Tedla et al.: "Serum Leukocyte Immunoglobulin-Like Receptor A3 (LILRA3) Is Increased in Patients with Multiple Sclerosis and Is a Strong Independent Indicator of Disease Severity; 6.7kbp LILRA3 Gene Deletion Is Not ..." in: PLoS ONE, Vol. 11, Issue 2, pp. e0149200, (2016) (PubMed).

Low, Ahrenstorf, Pommerenke, Habermann, Schughart, Ordóñez, Stripecke, Wilk, Witte: "TLR8 regulation of LILRA3 in monocytes is abrogated in human immunodeficiency virus infection and correlates to CD4 counts and virus loads." in: Retrovirology, Vol. 13, pp. 15, (2016) (PubMed).

Lee, Mitchell, Liu Lau, An, Rajeaskariah, Wasinger, Raftery, Bryant, Tedla: "Glycosylation in a mammalian expression system is critical for the production of functionally active leukocyte immunoglobulin-like receptor A3 protein." in: The Journal of biological chemistry, Vol. 288, Issue 46, pp. 32873-85, (2013) (PubMed).

An, Chandra, Piraino, Borges, Geczy, McNeil, Bryant, Tedla et al.: "Soluble LILRA3, a potential natural antiinflammatory protein, is increased in patients with rheumatoid arthritis and is tightly regulated by interleukin 10, tumor necrosis factor-alpha, and ..." in: The Journal of rheumatology, Vol. 37, Issue 8, pp. 1596-606, (2010) (PubMed).

Details zu LILRA3

Target: LILRA3 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3))

Andere Bezeichnung: LILRA3 (LILRA3 Produkte)

Synonyme: CD85E antikoerper, HM31 antikoerper, HM43 antikoerper, ILT-6 antikoerper, ILT6 antikoerper, LIR-4 antikoerper, LIR4 antikoerper, e3 antikoerper, leukocyte immunoglobulin like receptor A3 antikoerper, LILRA3 antikoerper

Hintergrund: Full Gene Name: leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
Synonyms: CD85E,HM31,HM43,ILT6,LIR-4,LIR4,e3

Gen-ID: 11026