Retinoid X Receptor alpha Antikörper

Produktnummer ABIN5647263

Produktdetails anti-Retinoid X Receptor alpha Antikörper

Target: Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Retinoid X Receptor alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity purified

Immunogen: A recombinant human protein corresponding to amino acids A226-T462 was used as the immunogen for the RXRA antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the RXRA antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the RXRA antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Retinoid X Receptor alpha

Target: Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

Andere Bezeichnung: RXRA / Retinoic X Receptor alpha (RXRA Produkte)

Synonyme: NR2B1 antikoerper, 9530071D11Rik antikoerper, Nr2b1 antikoerper, RXRalpha1 antikoerper, RXRalpha antikoerper, rxra-A antikoerper, xRXR alpha antikoerper, xrxra antikoerper, RXRA antikoerper, RXR alpha antikoerper, etID309731.5 antikoerper, rxr antikoerper, rxra antikoerper, rxrg antikoerper, RXRalpha-B antikoerper, retinoid X receptor alpha antikoerper, retinoid X receptor alpha L homeolog antikoerper, retinoid x receptor, alpha b antikoerper, retinoid X receptor, alpha a antikoerper, RXRA antikoerper, Rxra antikoerper, rxra.L antikoerper, CpipJ_CPIJ010249 antikoerper, rxrab antikoerper, rxraa antikoerper

Hintergrund: Retinoid X receptor alpha (RXR-alpha), also known as NR2B1 (nuclear receptor subfamily 2, group B, member 1) is a nuclear receptor that in humans is encoded by the RXRA gene. Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants.

UniProt: P19793

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Hepatitis C