PACSIN2 Antikörper (AA 342-371)

Produktnummer ABIN5647224

Produktdetails anti-PACSIN2 Antikörper

Target: PACSIN2 (Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2))

Bindungsspezifität: AA 342-371

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PACSIN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 342-371 from the human protein was used as the immunogen for the PACSIN2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western blot: 1:500-1:1000,IHC (FFPE): 1:50-100,Immunofluorescence: 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the PACSIN2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu PACSIN2

Target: PACSIN2 (Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2))

Andere Bezeichnung: PACSIN2 (PACSIN2 Produkte)

Synonyme: zgc:77519 antikoerper, PACSIN2 antikoerper, DKFZp459J1025 antikoerper, SDPII antikoerper, AI197433 antikoerper, sdpii antikoerper, SdpII antikoerper, protein kinase C and casein kinase substrate in neurons 2 antikoerper, protein kinase C and casein kinase substrate in neurons 2 S homeolog antikoerper, pacsin2 antikoerper, PACSIN2 antikoerper, Pacsin2 antikoerper, pacsin2.S antikoerper

Hintergrund: Protein kinase C and casein kinase substrate in neurons protein 2 is a lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle- mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.

UniProt: Q9UNF0