ALDH1A3 Antikörper

Produktnummer ABIN5647014

Produktdetails anti-ALDH1A3 Antikörper

Target: ALDH1A3 (Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALDH1A3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids N37-K154 from the human protein were used as the immunogen for the ALDH1A3 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the ALDH1A3 antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the ALDH1A3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu ALDH1A3

Target: ALDH1A3 (Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3))

Andere Bezeichnung: ALDH1A3 (ALDH1A3 Produkte)

Synonyme: RALDH3 antikoerper, ALDH1A3 antikoerper, ALDH1A6 antikoerper, ALDH6 antikoerper, MCOP8 antikoerper, Aldh6 antikoerper, V1 antikoerper, aldehyde dehydrogenase 1 family member A3 antikoerper, aldehyde dehydrogenase 1 family member A3 L homeolog antikoerper, aldehyde dehydrogenase 1 family, member A3 antikoerper, aldehyde dehydrogenase family 1, subfamily A3 antikoerper, ALDH1A3 antikoerper, aldh1a3.L antikoerper, aldh1a3 antikoerper, Aldh1a3 antikoerper

Hintergrund: Aldehyde dehydrogenase 1 family, member A3, also known as ALDH1A3 or retinaldehyde dehydrogenase 3 (RALDH3), is an enzyme that in humans is encoded by the ALDH1A3 gene. Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The enzyme encoded by this gene uses retinal as a substrate, either in a free or a cellular retinol-binding protein form. Mutations in this gene have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants.

UniProt: P47895

Pathways: Retinoic Acid Receptor Signaling Pathway