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PDHX Antikörper

PDHX Reaktivität: Human, Maus WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN357415
  • Target Alle PDHX Antikörper anzeigen
    PDHX (Pyruvate Dehydrogenase Complex, Component X (PDHX))
    Reaktivität
    • 23
    • 20
    • 17
    Human, Maus
    Wirt
    • 35
    • 3
    • 1
    • 1
    Kaninchen
    Klonalität
    • 39
    • 1
    Polyklonal
    Konjugat
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PDHX Antikörper ist unkonjugiert
    Applikation
    • 31
    • 13
    • 13
    • 7
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects PDX1.
    Aufreinigung
    Protein A column, followed by peptide affinity purification
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding T11 of human PDX1.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product PDHX Primärantikörper
  • Applikationshinweise
    ELISA 1: 1,000. Western blot 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Target
    PDHX (Pyruvate Dehydrogenase Complex, Component X (PDHX))
    Andere Bezeichnung
    PDHX / PDX1 (PDHX Produkte)
    Synonyme
    DLDBP antikoerper, E3BP antikoerper, OPDX antikoerper, PDX1 antikoerper, proX antikoerper, AI481367 antikoerper, E3bp antikoerper, Pdx1 antikoerper, Ac1164 antikoerper, zgc:66110 antikoerper, zgc:85977 antikoerper, MGC86218 antikoerper, PDHX antikoerper, DDBDRAFT_0168431 antikoerper, DDBDRAFT_0230192 antikoerper, DDB_0168431 antikoerper, DDB_0230192 antikoerper, pyruvate dehydrogenase complex component X antikoerper, pyruvate dehydrogenase complex, component X antikoerper, pyruvate dehydrogenase complex component X L homeolog antikoerper, E3-binding protein antikoerper, PDHX antikoerper, Pdhx antikoerper, pdhx antikoerper, pdhx.L antikoerper, pdhX antikoerper
    Hintergrund
    PDX1, located in the mitochondrial matrix, is required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex. Eukaryotic pyruvate dehydrogenase complexes are organized about a core consisting of the oligomeric dihydrolipoamide acetyl-transferase, around which are arranged multiple copies of pyruvate dehydrogenase, dihydrolipoamide dehydrogenase and protein X bound by noncovalent bonds. Defects in PDHX are a cause of lacticacidemia. PDX1 belongs to the 2-oxoacid dehydrogenase family and contains 1 lipoyl-binding domain.Synonyms: Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex, E3-binding protein, E3BP, Lipoyl-containing pyruvate dehydrogenase complex component X, Pyruvate dehydrogenase protein X component mitochondrial, proX
    Molekulargewicht
    54122 Da predicted from amino acid sequence. Theoretical pI: 8.80.
    Gen-ID
    8050, 9606
    UniProt
    O00330
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