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Filamin A Antikörper (AA 1-838)

FLNA Reaktivität: Human WB, ELISA, IHC (p), PLA Wirt: Maus Monoclonal 4E10-1B2 unconjugated
Produktnummer ABIN560922
  • Target Alle Filamin A (FLNA) Antikörper anzeigen
    Filamin A (FLNA) (Filamin A, alpha (FLNA))
    Bindungsspezifität
    • 15
    • 15
    • 13
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-838
    Reaktivität
    • 102
    • 33
    • 28
    • 3
    • 1
    • 1
    Human
    Wirt
    • 96
    • 5
    • 1
    Maus
    Klonalität
    • 86
    • 16
    Monoklonal
    Konjugat
    • 43
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser Filamin A Antikörper ist unkonjugiert
    Applikation
    • 51
    • 30
    • 28
    • 28
    • 28
    • 22
    • 12
    • 9
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Proximity Ligation Assay (PLA)
    Verwendungszweck
    Mouse monoclonal antibody raised against a full length recombinant FLNA.
    Sequenz
    MPSGKVAQPT ITDNKDGTVT VRYAPSEAGL HEMDIRYDNM HIPGSPLQFY VDYVNCGHVT AYGPGLTHGV VNKPATFTVN TKDAGEGGLS LAIEGPSKAE ISCTDNQDGT CSVSYLPVLP GDYSILVKYN EQHVPGSPFT ARVTGDDSMR MSHLKVGSAA DIPINISETD LSLLTATVVP PSGREEPCLL KRLRNGHVGI SFVPKETGEH LVHVKKNGQH VASSPIPVVI SQSEIGDASR VRVSGQGLHE GHTFEPAEFI IDTRDAGYGG LSLSIEGPSK VDINTEDLED GTCRVTYCPT EPGNYIINIK FADQHVPGSP FSVKVTGEGR VKESITRRRR APSVANVGSH CDLSLKIPEI SIQDMTAQVT SPSGKTHEAE IVEGENHTYC IRFVPAEMGT HTVSVKYKGQ HVPGSPFQFT VGPLGEGGAH KVRAGGPGLE RAEAGVPAEF SIWTREAGAG GLAIAVEGPS KAEISFEDRK DGSCGVAYVV QEPGDYEVSV KFNEEHIPDS PFVVPVASPS GDARRLTVSS LQESGLKVNQ PASFAVSLNG AKGAIDAKVH SPSGALEECY VTEIDQDKYA VRFIPRENGV YLIDVKFNGT HIPGSPFKIR VGEPGHGGDP GLVSAYGAGL EGGVTGNPAE FVVNTSNAGA GALSVTIDGP SKVKMDCQEC PEGYRVTYTP MAPGSYLISI KYGGPYHIGG SPFKAKVTGP RLVSNHSLHE TSSVFVDSLT KATCAPQHGA PGPGPADASK VVAKGLGLSK AYVGQKSSFT VDCSKAGNNM LLVGVHGPRT PCEEILVKHV GSRLYSVSYL LKDKGEYTLV VKWGDEHIPG SPYRVVVP
    Kreuzreaktivität
    Human
    Produktmerkmale
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    FLNA (AAH14654, 1 a.a. ~ 838 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Klon
    4E10-1B2
    Isotyp
    IgG1
    Top Product
    Discover our top product FLNA Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    In 1x PBS, pH 7.4
    Handhabung
    Aliquot to avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Mingione, Verdelli, Ferrero, Vaira, Guarnieri, Scillitani, Vicentini, Balza, Beretta, Terranegra, Vezzoli, Soldati, Corbetta: "Filamin A is reduced and contributes to the CASR sensitivity in human parathyroid tumors." in: Journal of molecular endocrinology, Vol. 58, Issue 2, pp. 91-103, (2016) (PubMed).

    Parrini, Mei, Pisanti, Catarzi, Pucatti, Bianchini, Mascalchi, Bertini, Morrone, Cavaliere, Guerrini: "Familial periventricular nodular heterotopia, epilepsy and Melnick-Needles Syndrome caused by a single FLNA mutation with combined gain-of-function and loss-of-function effects." in: Journal of medical genetics, Vol. 52, Issue 6, pp. 405-12, (2015) (PubMed).

    Bézie, Picarda, Tesson, Renaudin, Durand, Ménoret, Mérieau, Chiffoleau, Guillonneau, Caron, Anegon: "Fibrinogen-like protein 2/fibroleukin induces long-term allograft survival in a rat model through regulatory B cells." in: PLoS ONE, Vol. 10, Issue 3, pp. e0119686, (2015) (PubMed).

    Peverelli, Giardino, Treppiedi, Vitali, Cambiaghi, Locatelli, Lasio, Spada, Lania, Mantovani: "Filamin A (FLNA) plays an essential role in somatostatin receptor 2 (SST2) signaling and stabilization after agonist stimulation in human and rat somatotroph tumor cells." in: Endocrinology, Vol. 155, Issue 8, pp. 2932-41, (2014) (PubMed).

    Oegema, Hulst, Theuns-Valks, van Unen, Schot, Mancini, Schipper, de Wit, Sibbles, de Coo, Nanninga, Hofstra, Halley, Brooks: "Novel no-stop FLNA mutation causes multi-organ involvement in males." in: American journal of medical genetics. Part A, Vol. 161A, Issue 9, pp. 2376-84, (2013) (PubMed).

    Sakane, Alamir Mahmoud Abdallah, Nakano, Honda, Kitamura, Imoto, Matsushita, Sasaki: "Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 18, Issue 9, pp. 810-22, (2013) (PubMed).

    Peverelli, Mantovani, Vitali, Elli, Olgiati, Ferrero, Laws, Della Mina, Villa, Beck-Peccoz, Spada, Lania: "Filamin-A is essential for dopamine d2 receptor expression and signaling in tumorous lactotrophs." in: The Journal of clinical endocrinology and metabolism, Vol. 97, Issue 3, pp. 967-77, (2012) (PubMed).

    Valente, Logan, Mougou-Zerelli, Lee, Silhavy, Brancati, Iannicelli, Travaglini, Romani, Illi, Adams, Szymanska, Mazzotta, Lee, Tolentino, Swistun, Salpietro, Fede, Gabriel, Russ, Cibulskis, Sougnez et al.: "Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes. ..." in: Nature genetics, Vol. 42, Issue 7, pp. 619-25, (2010) (PubMed).

  • Target
    Filamin A (FLNA) (Filamin A, alpha (FLNA))
    Andere Bezeichnung
    FLNA (FLNA Produkte)
    Synonyme
    ABP-280 antikoerper, ABPX antikoerper, CSBS antikoerper, CVD1 antikoerper, FLN antikoerper, FLN-A antikoerper, FLN1 antikoerper, FMD antikoerper, MNS antikoerper, NHBP antikoerper, OPD antikoerper, OPD1 antikoerper, OPD2 antikoerper, XLVD antikoerper, XMVD antikoerper, fb98b06 antikoerper, wu:fb98b06 antikoerper, wu:fd09g03 antikoerper, wu:fd49a06 antikoerper, Dilp2 antikoerper, F730004A14Rik antikoerper, Fln1 antikoerper, filamin-1 antikoerper, RGD1560614 antikoerper, MGC147094 antikoerper, CG3937 antikoerper, Cher antikoerper, Dmel\\CG3937 antikoerper, Fil antikoerper, joy antikoerper, sko antikoerper, filamin A antikoerper, filamin A, alpha (actin binding protein 280) antikoerper, filamin, alpha antikoerper, filamin-A antikoerper, cheerio antikoerper, FLNA antikoerper, flna antikoerper, Flna antikoerper, LOC587317 antikoerper, cher antikoerper, LOC100380643 antikoerper
    Hintergrund
    Full Gene Name: filamin A, alpha (actin binding protein 280)
    Synonyms: ABP-280,ABPX,DKFZp434P031,FLN,FLN1,FMD,MNS,NHBP,OPD,OPD1,OPD2
    Gen-ID
    2316
    Pathways
    T-Zell Rezeptor Signalweg, Maintenance of Protein Location
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