CTH Antikörper (AA 1-405)

Produktnummer ABIN560522

Produktdetails anti-CTH Antikörper

Target: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Bindungsspezifität: AA 1-405

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CTH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: Mouse monoclonal antibody raised against a full length recombinant CTH.

Sequenz: MQEKDASSQG FLPHFQHFAT QAIHVGQDPE QWTSRAVVPP ISLSTTFKQG APGQHSGFEY SRSGNPTRNC LEKAVAALDG AKYCLAFASG LAATVTITHL LKAGDQIICM DDVYGGTNRY FRQVASEFGL KISFVDCSKI KLLEAAITPE TKLVWIETPT NPTQKVIDIE GCAHIVHKHG DIILVVDNTF MSPYFQRPLA LGADISMYSA TKYMNGRSDV VMGLVSVNCE SLHNRLRFLQ NSLGAVPSPI DCYLCNRGLK TLHVRMEKHF KNGMAVAQFL ESNPWVEKVI YPGLPSHPQH ELVKRQCTGC TGMVTFYIKG TLQHAEIFLK NLKLFTLAES LGGFESLAEL PAIMTHASVL KNDRDVLGIS DTLIRLSVGL EDEEDLLEDL DQALKAAHPP SGSHS

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: CTH (AAH15807, 1 a.a. ~ 405 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 2E12-1C10

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-CTH Antikörper (ABIN560522)

Grassi, Tyagi, Calvert, Gambari, Walker, Yu, Robinson, Li, Lisignoli, Vaccaro, Adams, Pacifici: "Hydrogen Sulfide Is a Novel Regulator of Bone Formation Implicated in the Bone Loss Induced by Estrogen Deficiency." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 31, Issue 5, pp. 949-63, (2016) (PubMed).

Dickhout, Carlisle, Jerome, Mohammed-Ali, Jiang, Yang, Mani, Garg, Banerjee, Kaufman, Maclean, Wang, Austin: "Integrated stress response modulates cellular redox state via induction of cystathionine ?-lyase: cross-talk between integrated stress response and thiol metabolism." in: The Journal of biological chemistry, Vol. 287, Issue 10, pp. 7603-14, (2012) (PubMed).

Maclean, Sikora, Kožich, Jiang, Greiner, Kraus, Krijt, Overdier, Collard, Brodsky, Meltesen, Crnic, Allen, Stabler, Elleder, Rozen, Patterson, Kraus: "A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine treatment." in: Molecular genetics and metabolism, Vol. 101, Issue 2-3, pp. 153-62, (2010) (PubMed).

dEmmanuele di Villa Bianca, Sorrentino, Maffia, Mirone, Imbimbo, Fusco, De Palma, Ignarro, Cirino: "Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 11, pp. 4513-8, (2009) (PubMed).

Zhang, Jiang, Fang, Yan, Song, Gupta, Schafer, Durante, Kruger, Yang, Wang: "Hyperhomocysteinemia promotes inflammatory monocyte generation and accelerates atherosclerosis in transgenic cystathionine beta-synthase-deficient mice." in: Circulation, Vol. 120, Issue 19, pp. 1893-902, (2009) (PubMed).

Details zu CTH

Target: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Andere Bezeichnung: CTH (CTH Produkte)

Synonyme: DYT17 antikoerper, DYT18 antikoerper, DYT9 antikoerper, EIG12 antikoerper, GLUT antikoerper, GLUT1 antikoerper, GLUT1DS antikoerper, HTLVR antikoerper, PED antikoerper, wu:fb48e03 antikoerper, wu:fb58d08 antikoerper, zgc:66001 antikoerper, zgc:85785 antikoerper, CTH antikoerper, 0610010I13Rik antikoerper, AI314617 antikoerper, BC019483 antikoerper, CSE antikoerper, Cys3 antikoerper, cysA antikoerper, SCQ11.03c antikoerper, DDBDRAFT_0190313 antikoerper, DDBDRAFT_0191318 antikoerper, DDB_0190313 antikoerper, DDB_0191318 antikoerper, H antikoerper, MGC75946 antikoerper, cystathionine gamma-lyase antikoerper, solute carrier family 2 member 1 antikoerper, cystathionase (cystathionine gamma-lyase) antikoerper, cystathionine gamma-lyase L homeolog antikoerper, CTH antikoerper, SLC2A1 antikoerper, cth antikoerper, Cth antikoerper, SCO3920 antikoerper, mlr1566 antikoerper, TA_RS00415 antikoerper, MAP_RS15640 antikoerper, SPO3344 antikoerper, CNN01730 antikoerper, Mmcs_1928 antikoerper, RHA1_RS31820 antikoerper, HNE_1212 antikoerper, MAV_3867 antikoerper, MSMEG_2394 antikoerper, Mvan_2142 antikoerper, SACE_6136 antikoerper, Mflv_4220 antikoerper, cysA antikoerper, cth.L antikoerper

Hintergrund: Full Gene Name: cystathionase (cystathionine gamma-lyase)
Synonyms: MGC9471

Gen-ID: 1491

Pathways: ER-Nucleus Signaling, Warburg Effekt