CTH Antikörper (AA 1-405)

Produktnummer ABIN560521

Produktdetails anti-CTH Antikörper

Target: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Bindungsspezifität: AA 1-405

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CTH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: Mouse monoclonal antibody raised against a full length recombinant CTH.

Sequenz: MQEKDASSQG FLPHFQHFAT QAIHVGQDPE QWTSRAVVPP ISLSTTFKQG APGQHSGFEY SRSGNPTRNC LEKAVAALDG AKYCLAFASG LAATVTITHL LKAGDQIICM DDVYGGTNRY FRQVASEFGL KISFVDCSKI KLLEAAITPE TKLVWIETPT NPTQKVIDIE GCAHIVHKHG DIILVVDNTF MSPYFQRPLA LGADISMYSA TKYMNGRSDV VMGLVSVNCE SLHNRLRFLQ NSLGAVPSPI DCYLCNRGLK TLHVRMEKHF KNGMAVAQFL ESNPWVEKVI YPGLPSHPQH ELVKRQCTGC TGMVTFYIKG TLQHAEIFLK NLKLFTLAES LGGFESLAEL PAIMTHASVL KNDRDVLGIS DTLIRLSVGL EDEEDLLEDL DQALKAAHPP SGSHS

Kreuzreaktivität: Meerschweinchen, Human, Ratte

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: CTH (AAH15807, 1 a.a. ~ 405 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 4E1-1B7

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-CTH Antikörper (ABIN560521)

Li, Li, Du, Wang, You, Wang, Xu, Cheng, Cao, Liu, Hu: "Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter." in: International journal of molecular sciences, Vol. 16, Issue 6, pp. 12560-77, (2015) (PubMed).

Xu, Du, Li, Xu, Wang, You, Liu, Wang, Cao, Liu, Hu: "Statins upregulate cystathionine ?-lyase transcription and H2S generation via activating Akt signaling in macrophage." in: Pharmacological research : the official journal of the Italian Pharmacological Society, Vol. 87, pp. 18-25, (2014) (PubMed).

Ida, Sawa, Ihara, Tsuchiya, Watanabe, Kumagai, Suematsu, Motohashi, Fujii, Matsunaga, Yamamoto, Ono, Devarie-Baez, Xian, Fukuto, Akaike: "Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 21, pp. 7606-11, (2014) (PubMed).

Yang, Zhao, Ju, Mani, Cao, Puukila, Khaper, Wu, Wang: "Hydrogen sulfide protects against cellular senescence via S-sulfhydration of Keap1 and activation of Nrf2." in: Antioxidants & redox signaling, Vol. 18, Issue 15, pp. 1906-19, (2013) (PubMed).

Mani, Li, Untereiner, Wu, Yang, Austin, Dickhout, Lhoták, Meng, Wang: "Decreased endogenous production of hydrogen sulfide accelerates atherosclerosis." in: Circulation, Vol. 127, Issue 25, pp. 2523-34, (2013) (PubMed).

Badiei, Rivers-Auty, Ang, Bhatia: "Inhibition of hydrogen sulfide production by gene silencing attenuates inflammatory activity of LPS-activated RAW264.7 cells." in: Applied microbiology and biotechnology, Vol. 97, Issue 17, pp. 7845-52, (2013) (PubMed).

Kasparek, Linden, Farrugia, Sarr: "Hydrogen sulfide modulates contractile function in rat jejunum." in: The Journal of surgical research, Vol. 175, Issue 2, pp. 234-42, (2012) (PubMed).

Yang, Pei, Cao, Wang: "MicroRNA-21 represses human cystathionine gamma-lyase expression by targeting at specificity protein-1 in smooth muscle cells." in: Journal of cellular physiology, Vol. 227, Issue 9, pp. 3192-200, (2012) (PubMed).

Yang, Li, Tang, Wu, Zhao, Cao, Xu, Wang: "Increased neointimal formation in cystathionine gamma-lyase deficient mice: role of hydrogen sulfide in ?5?1-integrin and matrix metalloproteinase-2 expression in smooth muscle cells." in: Journal of molecular and cellular cardiology, Vol. 52, Issue 3, pp. 677-88, (2012) (PubMed).

Dufton, Natividad, Verdu, Wallace: "Hydrogen sulfide and resolution of acute inflammation: A comparative study utilizing a novel fluorescent probe." in: Scientific reports, Vol. 2, pp. 499, (2012) (PubMed).

Wu, Teng, Yang, Wu, Wang: "Hydrogen sulfide inhibits the translational expression of hypoxia-inducible factor-1?." in: British journal of pharmacology, Vol. 167, Issue 7, pp. 1492-505, (2012) (PubMed).

Fu, Zhang, Yang, Wang: "Is cystathionine gamma-lyase protein expressed in the heart?" in: Biochemical and biophysical research communications, Vol. 428, Issue 4, pp. 469-74, (2012) (PubMed).

Holwerda, Bos, Rajakumar, Ris-Stalpers, van Pampus, Timmer, Erwich, Faas, van Goor, Lely: "Hydrogen sulfide producing enzymes in pregnancy and preeclampsia." in: Placenta, Vol. 33, Issue 6, pp. 518-21, (2012) (PubMed).

Yang, Pei, Teng, Cao, Wang: "Specificity protein-1 as a critical regulator of human cystathionine gamma-lyase in smooth muscle cells." in: The Journal of biological chemistry, Vol. 286, Issue 30, pp. 26450-60, (2011) (PubMed).

Li, Mao, Hei, Zhang, Wen, Zhang, Qiu, Qiao: "Protective role of hydrogen sulfide against noise-induced cochlear damage: a chronic intracochlear infusion model." in: PLoS ONE, Vol. 6, Issue 10, pp. e26728, (2011) (PubMed).

Martin, McKnight, Dicay, Coffin, Ferraz, Wallace: "Hydrogen sulphide synthesis in the rat and mouse gastrointestinal tract." in: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, Vol. 42, Issue 2, pp. 103-9, (2010) (PubMed).

Feng, Chen, Zhao, Tang, Jiang, Geng: "Hydrogen sulfide from adipose tissue is a novel insulin resistance regulator." in: Biochemical and biophysical research communications, Vol. 380, Issue 1, pp. 153-9, (2009) (PubMed).

Wallace, Vong, McKnight, Dicay, Martin: "Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats." in: Gastroenterology, Vol. 137, Issue 2, pp. 569-78, 578.e1, (2009) (PubMed).

Fu, Liu, Geng, Fang, Tang: "Hydrogen sulfide protects rat lung from ischemia-reperfusion injury." in: Life sciences, Vol. 82, Issue 23-24, pp. 1196-202, (2008) (PubMed).

Wallace, Dicay, McKnight, Martin: "Hydrogen sulfide enhances ulcer healing in rats." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 14, pp. 4070-6, (2007) (PubMed).

Details zu CTH

Target: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Andere Bezeichnung: CTH (CTH Produkte)

Synonyme: DYT17 antikoerper, DYT18 antikoerper, DYT9 antikoerper, EIG12 antikoerper, GLUT antikoerper, GLUT1 antikoerper, GLUT1DS antikoerper, HTLVR antikoerper, PED antikoerper, wu:fb48e03 antikoerper, wu:fb58d08 antikoerper, zgc:66001 antikoerper, zgc:85785 antikoerper, CTH antikoerper, 0610010I13Rik antikoerper, AI314617 antikoerper, BC019483 antikoerper, CSE antikoerper, Cys3 antikoerper, cysA antikoerper, SCQ11.03c antikoerper, DDBDRAFT_0190313 antikoerper, DDBDRAFT_0191318 antikoerper, DDB_0190313 antikoerper, DDB_0191318 antikoerper, H antikoerper, MGC75946 antikoerper, cystathionine gamma-lyase antikoerper, solute carrier family 2 member 1 antikoerper, cystathionase (cystathionine gamma-lyase) antikoerper, cystathionine gamma-lyase L homeolog antikoerper, CTH antikoerper, SLC2A1 antikoerper, cth antikoerper, Cth antikoerper, SCO3920 antikoerper, mlr1566 antikoerper, TA_RS00415 antikoerper, MAP_RS15640 antikoerper, SPO3344 antikoerper, CNN01730 antikoerper, Mmcs_1928 antikoerper, RHA1_RS31820 antikoerper, HNE_1212 antikoerper, MAV_3867 antikoerper, MSMEG_2394 antikoerper, Mvan_2142 antikoerper, SACE_6136 antikoerper, Mflv_4220 antikoerper, cysA antikoerper, cth.L antikoerper

Hintergrund: Full Gene Name: cystathionase (cystathionine gamma-lyase)
Synonyms: MGC9471

Gen-ID: 1491

Pathways: ER-Nucleus Signaling, Warburg Effekt