SHP1 Antikörper (pTyr536)

Produktnummer ABIN5586488

Produktdetails anti-SHP1 Antikörper

Target: SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

Bindungsspezifität: pTyr536

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SHP1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic phosphopeptide of PTPN6.

Sequenz: S-E-Yp-G-N

Kreuzreaktivität: Human, Maus, Ratte

Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Y536 of human PTPN6.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:100-1:200)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: In PBS (without Mg²⁺ and Ca²⁺), 150 mM NaCl, pH 7.4 (50 % glycerol, 0.02 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-SHP1 Antikörper (ABIN5586488)

Sauer, Herbst, Diekmann, Rudd, Kardinal: "SHP-1 Acts as a Key Regulator of Alloresponses by Modulating LFA-1-Mediated Adhesion in Primary Murine T Cells." in: Molecular and cellular biology, Vol. 36, Issue 24, pp. 3113-3127, (2016) (PubMed).

Details zu SHP1

Target: SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

Andere Bezeichnung: PTPN6 (PTPN6 Produkte)

Synonyme: HCPH antikoerper, HPTP1C antikoerper, PTP-1C antikoerper, SH-PTP1 antikoerper, SHP-1 antikoerper, SHP-1L antikoerper, SHP1 antikoerper, DRPLA antikoerper, Hcph antikoerper, Ptp1C antikoerper, me antikoerper, motheaten antikoerper, Ptph6 antikoerper, Shp-1 antikoerper, fj22f05 antikoerper, wu:fj22f05 antikoerper, zgc:55501 antikoerper, ptpn6 antikoerper, protein tyrosine phosphatase, non-receptor type 6 antikoerper, protein tyrosine phosphatase, non-receptor type 6 L homeolog antikoerper, PTPN6 antikoerper, Ptpn6 antikoerper, ptpn6 antikoerper, ptpn6.L antikoerper

Hintergrund: Full Gene Name: protein tyrosine phosphatase, non-receptor type 6
Synonyms: HCP,HCPH,HPTP1C,PTP-1C,SH-PTP1,SHP-1,SHP-1L,SHP1

Gen-ID: 5777

Pathways: JAK-STAT Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling