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SLC7A8 Antikörper

SLC7A8 Reaktivität: Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5564261
  • Target Alle SLC7A8 Antikörper anzeigen
    SLC7A8 (Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8))
    Reaktivität
    • 13
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 9
    • 4
    Kaninchen
    Klonalität
    • 9
    • 4
    Polyklonal
    Konjugat
    • 13
    Dieser SLC7A8 Antikörper ist unkonjugiert
    Applikation
    • 12
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    Recognizes mouse and rat Slc7a8. Has been reported to work in human samples (Wirth,et al.; 2009), but was not tested in-house.Detects a -50kDa Slc7a8 band in wild type mouse brain, kidney, jejunum, ileum and othertissues, which is absent in knock-out animals. ln some tissues the antibody detects anadditional unknown 38kDa band.
    Kreuzreaktivität (Details)
    Other species not tested.Detects a ~50 kDa Slc7a8 band in wild type mouse brain, kidney, jejunum, ileum and other tissues, which is absent in knock-out animals. In some tissues the antibody detects an additional unknown 38 kDa band.
    Aufreinigung
    Antigen affinity purified.
    Immunogen
    Synthetic peptide corresponding to a partial sequence of mouse Slc7a8 (Q9QXW9).
    Top Product
    Discover our top product SLC7A8 Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    In PBS containing 1 mg/mL BSA and 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Haltbarkeit
    12 months
  • Target
    SLC7A8 (Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8))
    Andere Bezeichnung
    Slc7a8 [Lat2] (SLC7A8 Produkte)
    Synonyme
    LAT2 antikoerper, LPI-PC1 antikoerper, Lat2 antikoerper, Lat4 antikoerper, XAA2 antikoerper, lat2 antikoerper, lpi-pc1 antikoerper, 4F2LC-5 antikoerper, AA408822 antikoerper, si:ch211-14a17.3 antikoerper, si:zc14a17.3 antikoerper, slc7a8 antikoerper, solute carrier family 7 member 8 antikoerper, solute carrier family 7 member 8 L homeolog antikoerper, solute carrier family 7 (amino acid transporter, L-type), member 8 antikoerper, solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 antikoerper, solute carrier family 7 (amino acid transporter light chain, L system), member 8b antikoerper, SLC7A8 antikoerper, Slc7a8 antikoerper, slc7a8.L antikoerper, slc7a8 antikoerper, slc7a8b antikoerper
    Hintergrund
    L-type amino acid transporter (LAT) family members are Na(+)-independent transporters, which deliver neutral amino acids into cells. The four LATs, LAT1 (SLC7A5), LAT2 (SLC7A8), LAT3 (SLC43A1) and LAT4 (SLC43A2) are responsible for the majority of cellular leucine uptake. They show increased expression in many cancers and are critical for control of protein translation and cell growth through the mTORC1 pathway. The increased transporter expression observed in cancers is regulated by transcriptional pathways such as hormone receptors, c-myc and nutrient starvation responses.
    UniProt
    Q9QXW9
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