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TSPY1 Antikörper (C-Term, Isoform 1)

TSPY1 Reaktivität: Human, Maus WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1450020
  • Target Alle TSPY1 Antikörper anzeigen
    TSPY1 (Testis Specific Protein, Y-Linked 1 (TSPY1))
    Bindungsspezifität
    • 12
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term, Isoform 1
    Reaktivität
    Human, Maus
    Wirt
    • 28
    • 3
    Kaninchen
    Klonalität
    • 29
    • 2
    Polyklonal
    Konjugat
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TSPY1 Antikörper ist unkonjugiert
    Applikation
    • 23
    • 19
    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    Rabbit polyclonal TSPY1S antibody was raised against a 13 amino acid peptide near the carboxy terminus of human TSPY1S.
    Isotyp
    IgG
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  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody (in aliquots) at -20 °C.
  • Target
    TSPY1 (Testis Specific Protein, Y-Linked 1 (TSPY1))
    Andere Bezeichnung
    TSPY1 / TSPY (TSPY1 Produkte)
    Synonyme
    CT78 antikoerper, DYS14 antikoerper, TSPY antikoerper, pJA923 antikoerper, Tspy antikoerper, TSPY-M1 antikoerper, TSPY1 antikoerper, testis specific protein, Y-linked 1 antikoerper, TSPY1 antikoerper, Tspy1 antikoerper, TSPY antikoerper
    Hintergrund
    Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.Synonyms: CT78, Cancer/testis antigen 78, Testis-specific Y-encoded protein 1
    Molekulargewicht
    32 kDa
    Gen-ID
    7258
    NCBI Accession
    NP_001184171
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