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PLA1A Antikörper (C-Term)

PLA1A Reaktivität: Human, Ratte WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1449969
  • Target Alle PLA1A Antikörper anzeigen
    PLA1A (Phospholipase A1 Member A (PLA1A))
    Bindungsspezifität
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 35
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte
    Wirt
    • 31
    • 4
    Kaninchen
    Klonalität
    • 34
    • 1
    Polyklonal
    Konjugat
    • 18
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PLA1A Antikörper ist unkonjugiert
    Applikation
    • 24
    • 17
    • 13
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, Rat.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    17 amino acid synthetic peptide near the carboxy terminus of Human PLA1A
    Isotyp
    IgG
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    Discover our top product PLA1A Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    PLA1A (Phospholipase A1 Member A (PLA1A))
    Andere Bezeichnung
    PLA1A (PLA1A Produkte)
    Synonyme
    PS-PLA1 antikoerper, PSPLA1 antikoerper, AA986889 antikoerper, Ps-pla1 antikoerper, Pspla1 antikoerper, wu:fi26h09 antikoerper, zgc:77160 antikoerper, AH antikoerper, ARWH2 antikoerper, LAH2 antikoerper, LPDLR antikoerper, PLA1B antikoerper, mPA-PLA1 antikoerper, phospholipase A1 member A antikoerper, lipase H antikoerper, PLA1A antikoerper, Pla1a antikoerper, pla1a antikoerper, CpipJ_CPIJ002492 antikoerper, CpipJ_CPIJ007883 antikoerper, LIPH antikoerper
    Hintergrund
    PLA1A is a phospholipase that hydrolyzes fatty acids at the sn-1 position of phosphatidylserine and 1-acyl-2-lysophosphatidylserine. This secreted protein hydrolyzes phosphatidylserine (PS) in liposomes and can also hydrolyze PS in apoptotic cells and activate platelets where the resulting 2-acyl-lysophosphatidylserine acts as a lipid mediator for mast cells, T cells, and neural cells, suggesting that a major function of PLA1A may be the production of lysophospholipid mediators. PLA1A is upregulated in rat peripheral blood cells bearing long-term surviving cardiac allograft. PLA1A is also expressed in human THP-1-derived macrophages and this expression is upregulated in cells treated with lipopolysaccharide, a TLR4 ligand. This upregulation is inhibited with corticosteroids, which are often used at high dosages to suppress chronic allograft rejection.Synonyms: NMD, PSPLA1, Phospholipase A1 member A
    Molekulargewicht
    50 kDa
    Gen-ID
    51365
    NCBI Accession
    NP_056984
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