PLA1A Antikörper (C-Term)
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- Target Alle PLA1A Antikörper anzeigen
- PLA1A (Phospholipase A1 Member A (PLA1A))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PLA1A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, Rat.
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- 17 amino acid synthetic peptide near the carboxy terminus of Human PLA1A
- Isotyp
- IgG
- Top Product
- Discover our top product PLA1A Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % Sodium Azide as preservative
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- PLA1A (Phospholipase A1 Member A (PLA1A))
- Andere Bezeichnung
- PLA1A (PLA1A Produkte)
- Synonyme
- PS-PLA1 antikoerper, PSPLA1 antikoerper, AA986889 antikoerper, Ps-pla1 antikoerper, Pspla1 antikoerper, wu:fi26h09 antikoerper, zgc:77160 antikoerper, AH antikoerper, ARWH2 antikoerper, LAH2 antikoerper, LPDLR antikoerper, PLA1B antikoerper, mPA-PLA1 antikoerper, phospholipase A1 member A antikoerper, lipase H antikoerper, PLA1A antikoerper, Pla1a antikoerper, pla1a antikoerper, CpipJ_CPIJ002492 antikoerper, CpipJ_CPIJ007883 antikoerper, LIPH antikoerper
- Hintergrund
- PLA1A is a phospholipase that hydrolyzes fatty acids at the sn-1 position of phosphatidylserine and 1-acyl-2-lysophosphatidylserine. This secreted protein hydrolyzes phosphatidylserine (PS) in liposomes and can also hydrolyze PS in apoptotic cells and activate platelets where the resulting 2-acyl-lysophosphatidylserine acts as a lipid mediator for mast cells, T cells, and neural cells, suggesting that a major function of PLA1A may be the production of lysophospholipid mediators. PLA1A is upregulated in rat peripheral blood cells bearing long-term surviving cardiac allograft. PLA1A is also expressed in human THP-1-derived macrophages and this expression is upregulated in cells treated with lipopolysaccharide, a TLR4 ligand. This upregulation is inhibited with corticosteroids, which are often used at high dosages to suppress chronic allograft rejection.Synonyms: NMD, PSPLA1, Phospholipase A1 member A
- Molekulargewicht
- 50 kDa
- Gen-ID
- 51365
- NCBI Accession
- NP_056984
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