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TTBK2 Antikörper (C-Term)

TTBK2 Reaktivität: Human IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1449960
  • Target Alle TTBK2 Antikörper anzeigen
    TTBK2 (tau Tubulin Kinase 2 (TTBK2))
    Bindungsspezifität
    • 15
    • 9
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    C-Term
    Reaktivität
    • 46
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 43
    • 3
    Kaninchen
    Klonalität
    • 45
    • 1
    Polyklonal
    Konjugat
    • 22
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TTBK2 Antikörper ist unkonjugiert
    Applikation
    • 42
    • 22
    • 21
    • 13
    • 13
    • 13
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    18 amino acid synthetic peptide near the carboxy terminus of Human TTBK2
    Isotyp
    IgG
    Top Product
    Discover our top product TTBK2 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    TTBK2 (tau Tubulin Kinase 2 (TTBK2))
    Andere Bezeichnung
    TTBK2 (TTBK2 Produkte)
    Synonyme
    ttbk antikoerper, MGC146331 antikoerper, 2610507N02Rik antikoerper, AI326283 antikoerper, B930008N24Rik antikoerper, TTK antikoerper, Ttbk antikoerper, Ttbk1 antikoerper, mKIAA0847 antikoerper, SCA11 antikoerper, TTBK antikoerper, tau tubulin kinase 2 antikoerper, TTBK2 antikoerper, ttbk2 antikoerper, Ttbk2 antikoerper
    Hintergrund
    Tau tubulin kinase (TTBK2) is a serine/threonine kinase whose substrates are thought to include the tau and tubulin proteins. Mutations in the TTBK2 gene cause spinocerebellar ataxia type 11 (SCA11), a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem. Recent studies have shown that increased levels of TTBK2 expression in kidney carcinoma and melanoma cell lines increases resistance to the chemotherapeutic agent Sunitinib, and that reduction of TTBK2 though the use of siRNA sensitized these cell lines to the effects of Sunitib, suggesting that TTBK2 can be used as a resistance marker as well a potential target to overcome resistance.Synonyms: KIAA0847, Tau-tubulin kinase 2
    Gen-ID
    146057
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