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CRLF2 Antikörper (Center)

CRLF2 Reaktivität: Maus WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN501085
  • Target Alle CRLF2 Antikörper anzeigen
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    Bindungsspezifität
    • 15
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reaktivität
    • 39
    • 25
    • 21
    Maus
    Wirt
    • 43
    • 17
    • 3
    Kaninchen
    Klonalität
    • 46
    • 17
    Polyklonal
    Konjugat
    • 21
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser CRLF2 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 26
    • 26
    • 15
    • 10
    • 9
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects CRLF2.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Mouse
    Aufreinigung
    Peptide affinity chromatography
    Immunogen
    TSLP receptor antibody was raised against a 21 amino acid peptide from near the center of mouse TSLP receptor.
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    ELISA. Western blot: 0.5 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    Andere Bezeichnung
    CRLF2 (CRLF2 Produkte)
    Synonyme
    CRLF2 antikoerper, CRL2 antikoerper, CRLF2Y antikoerper, TSLPR antikoerper, CRLM2 antikoerper, Ly114 antikoerper, Tpte2 antikoerper, Tslpr antikoerper, Crl2 antikoerper, cytokine receptor like factor 2 antikoerper, cytokine receptor-like factor 2 antikoerper, CRLF2 antikoerper, Crlf2 antikoerper
    Hintergrund
    Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. It is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Its receptor TSLP-R will bind TSLP in a low-affinity fashion in transfected cells, co-transfection with IL-7R-alpha cDNA results in high-affinity binding and a functional heteromeric complex. This heteromeric receptor requires stat5 for TSLP-mediated signal transduction and is inhibited by SOCS-1. The approximately 75 kDa band seen in the immunoblot may be a post-translationally modified form of TSLP-R.Synonyms: Cytokine receptor-like 2, Cytokine receptor-like factor 2, IL-XR, ILXR, TSLPR, Thymic stromal lymphopoietin protein receptor
    Gen-ID
    57914
    NCBI Accession
    NP_057924
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