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FBXO43 Antikörper (C-Term)

FBXO43 Reaktivität: Human WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN499982
  • Target Alle FBXO43 Antikörper anzeigen
    FBXO43 (F-Box Protein 43 (FBXO43))
    Bindungsspezifität
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 10
    • 3
    • 2
    • 1
    Human
    Wirt
    • 9
    • 2
    • 1
    Kaninchen
    Klonalität
    • 10
    • 2
    Polyklonal
    Konjugat
    • 12
    Dieser FBXO43 Antikörper ist unkonjugiert
    Applikation
    • 10
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    IL-1RAcP antibody was raised against a peptide corresponding to amino acids 525 to 540 of human IL-1RAcP, which is identical to those of mouse and rat origins. This polyclonal antibody has no cross activity to other members in the IL-1 receptor family.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    Human IL-1RAcP (C-Terminus 2) Peptide
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    ELISA. Western Blot: 1/1000 to 1/2000 dilution. An approximately 66 kDa band can be detected.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
  • Target
    FBXO43 (F-Box Protein 43 (FBXO43))
    Andere Bezeichnung
    FBXO43 (FBXO43 Produkte)
    Synonyme
    EMI2 antikoerper, ERP1 antikoerper, FBX43 antikoerper, 4930533G20Rik antikoerper, Emi2 antikoerper, emi2 antikoerper, erp1 antikoerper, Xerp1 antikoerper, zgc:66488 antikoerper, F-box protein 43 antikoerper, F-box protein 43 L homeolog antikoerper, FBXO43 antikoerper, Fbxo43 antikoerper, fbxo43 antikoerper, fbxo43.L antikoerper
    Hintergrund
    The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP) (1). IL-1RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NFkappa-B inducing kinae (NIK) and of NF-kappaB, recruits to the IL-1R complex through IL-1RAcP (2). IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP (3,4). Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.Synonyms: EMI2, Endogenous meiotic inhibitor 2, F-box only protein 43, FBP5B
    Gen-ID
    100101275
    UniProt
    Q8AXF4
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