GFRA3 Antikörper (Intermediate Domain)

Produktnummer ABIN499887

Produktdetails anti-GFRA3 Antikörper

Target: GFRA3 (GDNF Family Receptor alpha 3 (GFRA3))

Bindungsspezifität: Intermediate Domain

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFRA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: GFR alpha 3 antibody was raised against a peptide corresponding to amino acids from 347 to 360 of murine GFR alpha 3.

Aufreinigung: DEAE

Immunogen: Human GFR alpha 3 (Intermediate Domain) Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1/500 to 1/1000. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu GFRA3

Target: GFRA3 (GDNF Family Receptor alpha 3 (GFRA3))

Andere Bezeichnung: GFRA3 / GDNFR-alpha 3 (GFRA3 Produkte)

Synonyme: GFRA3 antikoerper, GFRalpha3 antikoerper, Y15110 antikoerper, GDNF family receptor alpha 3 antikoerper, glial cell line derived neurotrophic factor family receptor alpha 3 antikoerper, Gfra3 antikoerper, GFRA3 antikoerper

Hintergrund: Members of the glial cell line-derived neurotrophic factor (GDNF) family including GDNF and neurturin (NTN) play essential roles in the control of vertebrate neuron survival and differentiation. A new member of the GDNF family was recently identified and designated persephin. Physiological responses to these neurotrophic factors require two receptor subunits, the novel glycosylphosphadidylinositol linked protein GFRalpha and Ret receptor tyrosine kinase GFRbeta (2). Following the findings of GFR?-1 and -2, a novel receptor in GFRalpha family was identified very recently from human and mouse and designated GFRalpha-3. GFRalpha-3 binds persephin, thus, persephin, GFRalpha-3, and Ret PTK form a complex to transduce persephin signal and to mediate persephin function.Synonyms: GDNF family receptor alpha-3, GDNF receptor alpha-3, GFR-alpha-3

Gen-ID: 14587

UniProt: O35118