Growth Differentiation Factor 6 (GDF6) (C-Term) Antikörper

Details zu Produkt Nr. ABIN5554819, Anbieter: Anmelden zum Anzeigen
Antigen
  • gdf6
  • rdr
  • sb:cb278
  • BMP13
  • CDMP2
  • KFM
  • KFS
  • KFS1
  • KFSL
  • LCA17
  • MCOP4
  • MCOPCB6
  • SCDO4
  • SGM1
  • GDF16
  • gdf16
  • CDMP-2
  • GDF6/7
  • growth differentiation factor 6
  • growth differentiation factor 6a
  • growth differentiation factor 7
  • GDF6
  • gdf6
  • gdf6a
  • Gdf6
  • GDF7
Epitop
C-Term
9
5
4
3
3
3
2
2
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
50
43
27
2
2
Wirt
Kaninchen
58
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
44
16
15
13
10
9
3
3
2
1
Optionen
Hersteller
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Immunogen GDF6 antibody was raised against a 17 amino acid peptide near the carboxy terminus of the human GDF6.
Isotyp IgG
Spezifität This antibody reacts to GDF6.
Reinigung Affinity chromatography purified via peptide column
Antigen
Andere Bezeichnung BMP13 / GDF6 (GDF6 Antibody Abstract)
Hintergrund Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. Both GDF6 and GDF7 are closely related to GDF5 which has been shown to induce activation of plasminogen activator, thereby inducing angiogenesis. It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation. In Xenopus, GDF6 is expressed at the edge of the neural plate and within the anterior neural plate including the eye fields. GDF6 is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. It may regulate patterning of the ectoderm by interacting with bone morphogenetic proteins (BMPs), and control eye development. Mutations in this gene result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), a congenital disorder of spinal segmentation.Synonyms: Bone Morphogenetic Protein 13, CDMP2, Cartilage Derived Morphogenetic Protein 2, GDF-16, GDF-6, GDF16
Gen-ID 392255
NCBI Accession NP_001001557
UniProt Q6KF10
Applikations-hinweise ELISA. Western Blot: 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Buffer PBS containing 0.02 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C.
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