MGC76180 antikoerper, MGC80733 antikoerper, 4931430I01Rik antikoerper, AI452351 antikoerper, PP3051 antikoerper, mitocalcin antikoerper, MST133 antikoerper, MSTP133 antikoerper, SWS2 antikoerper, RGD1559565 antikoerper, EF-hand domain family member D1 antikoerper, EF-hand domain family member D1 L homeolog antikoerper, EF-hand domain family, member D1 antikoerper, EF hand domain containing 1 antikoerper, efhd1 antikoerper, EFHD1 antikoerper, efhd1.L antikoerper, Efhd1 antikoerper
Hintergrund
EFHD1, also known as Swiprosin-2 or SWS2, is an EF-hand and coiled-coil-containing adaptor protein identified in a subtractive hybridization study using a neuronal cell line established from the cerebellum of an adult p53-null mouse, however further study indicated no difference in normal mice. Its mRNA is widely expressed, with its expression in brain undetectable at embryonic stages, with increasing levels from postnatal to adult development. In situ hybridization showed expression in neurons but not white matter of the cerebellum and cerebrum. EHFD1 is also highly expressed in testes, ovary, and the collecting ducts of the kidney, suggesting that in non-neuronal cells, EFHD1 may be involved in gametogenesis and water-reabsorbtion.Synonyms: EF-hand domain-containing protein 1, EF-hand domain-containing protein D1, PP3051, SWS2, Swiprosin 2, Swiprosin-2