Angiotensin II Type 2 Receptor Antikörper (Center)

Produktnummer ABIN499231

Produktdetails anti-Angiotensin II Type 2 Receptor Antikörper

Target: Angiotensin II Type 2 Receptor (AGTR2) (Angiotensin II Receptor, Type 2 (AGTR2))

Bindungsspezifität: Center

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Angiotensin II Type 2 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to AGTR2.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: AGTR2 antibody was raised against a 16 amino acid peptide from near the center of human AGTR2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: AGTR2 antibody can be used for detection of AGTR2 at 0.5 - 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu Angiotensin II Type 2 Receptor

Target: Angiotensin II Type 2 Receptor (AGTR2) (Angiotensin II Receptor, Type 2 (AGTR2))

Andere Bezeichnung: Type-2 Angiotensin II Receptor (AT2) (AGTR2 Produkte)

Synonyme: AT2 antikoerper, ATGR2 antikoerper, MRX88 antikoerper, AI316812 antikoerper, AW107640 antikoerper, AT2-R antikoerper, AT2R antikoerper, AT₂R antikoerper, at2 antikoerper, zgc:113016 antikoerper, AGTR2 antikoerper, angiotensin II receptor type 2 antikoerper, angiotensin II receptor, type 2 antikoerper, AGTR2 antikoerper, Agtr2 antikoerper, agtr2 antikoerper

Hintergrund: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.Synonyms: AGTR2

Gen-ID: 186

UniProt: P50052

Pathways: ACE Inhibitor Pathway, Hormone Transport, Regulation of Systemic Arterial Blood Pressure by Hormones