ANAPC11 Antikörper (Center)

Produktnummer ABIN783600

Produktdetails anti-ANAPC11 Antikörper

Target: ANAPC11 (Anaphase Promoting Complex Subunit 11 (ANAPC11))

Bindungsspezifität: Center

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANAPC11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid peptide near the center of human APC11

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu ANAPC11

Target: ANAPC11 (Anaphase Promoting Complex Subunit 11 (ANAPC11))

Andere Bezeichnung: APC11 / ANAPC11 (ANAPC11 Produkte)

Synonyme: APC11 antikoerper, Apc11p antikoerper, anapc11 antikoerper, RGD1561880 antikoerper, F10A16.17 antikoerper, F10A16_17 antikoerper, anaphase-promoting complex/cyclosome 11 antikoerper, DDBDRAFT_0187183 antikoerper, DDBDRAFT_0231277 antikoerper, DDB_0187183 antikoerper, DDB_0231277 antikoerper, 1110011I19Rik antikoerper, R75218 antikoerper, zgc:153671 antikoerper, si:dkey-237i9.4 antikoerper, anaphase promoting complex subunit 11 antikoerper, anaphase promoting complex subunit 11 L homeolog antikoerper, anaphase-promoting complex/cyclosome 11 antikoerper, anaphase-promoting complex subunit Apc11 antikoerper, ubiquitin-protein ligase Anaphase Promoting Complex antikoerper, hypothetical protein antikoerper, predicted protein antikoerper, anaphase-promoting complex subunit 11 antikoerper, APC11 anaphase promoting complex subunit 11 homolog (yeast) antikoerper, ANAPC11 antikoerper, anapc11.L antikoerper, anapc11 antikoerper, Anapc11 antikoerper, APC11 antikoerper, apc11 antikoerper, CAALFM_CR10610CA antikoerper, LOC9320604 antikoerper, LOC692923 antikoerper

Hintergrund: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC11 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC11, together with APC2 and Ubc4, form the minimal APC ubiquitin ligase module.Synonyms: Anaphase-promoting complex subunit 11, Cyclosome subunit 11, HSPC214, Hepatocellular carcinoma-associated RING finger protein

Gen-ID: 51529

NCBI Accession: NP_001002244

UniProt: Q9NYG5