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RABGEF1 Antikörper (Center)

RABGEF1 Reaktivität: Human, Maus, Ratte WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN783421
  • Target Alle RABGEF1 Antikörper anzeigen
    RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))
    Bindungsspezifität
    • 15
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    Center
    Reaktivität
    • 30
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 28
    • 2
    Kaninchen
    Klonalität
    • 30
    Polyklonal
    Konjugat
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RABGEF1 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 13
    • 13
    • 9
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects RABGEF1 at Center. At least four isoforms of RABEX5 are known to exist, this antibody will recognize all four. RABEX5 antibody is predicted to not cross-react with other LRRFIP family members.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse, rat
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    19 amino acid peptide near the center terminus of human RABEX5
    Top Product
    Discover our top product RABGEF1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))
    Andere Bezeichnung
    RABGEF1 (RABGEF1 Produkte)
    Synonyme
    Rab5ef antikoerper, Rabex5 antikoerper, Rin2 antikoerper, RABEX5 antikoerper, rabex-5 antikoerper, rabgef1 antikoerper, RAB guanine nucleotide exchange factor (GEF) 1 antikoerper, RAB guanine nucleotide exchange factor 1 antikoerper, RAB guanine nucleotide exchange factor (GEF) 1 L homeolog antikoerper, Rabgef1 antikoerper, RABGEF1 antikoerper, rabgef1.L antikoerper
    Hintergrund
    RABEX5 is a guanine nucleotide exchange factor (GEF) that forms a complex with rabaptin-5 and specifically activates Rab5, a small GTPase that plays an essential role in endocytic traffic. RABEX-5 is thought to also interact with another member of the Rab family, Rab22, which targets RABEX5 to early endosomes, allowing it to activate Rab5 and thereby promote Rab5-mediated endosome fusion.Synonyms: RABEX5, RAP1, Rab5 GDP/GTP exchange factor, Rabaptin-5-associated exchange factor for Rab5, Rabex-5
    Gen-ID
    27342
    NCBI Accession
    NP_055319
    UniProt
    Q9UJ41
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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