CLCN2 Antikörper (Internal Region)

Produktnummer ABIN615956

Produktdetails anti-CLCN2 Antikörper

Target: CLCN2 (Chloride Channel 2 (CLCN2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CLCN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequenz: QQLDEPVNFS DCK

Spezifität: This antibody is expected to recognize all reported isoforms (NP_004357.3, NP_001164558.1, NP_001164559.1, NP_001164560.1).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog), Cow, Rabbit .
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_004357.3. Genename: CLCN2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CLCN2

Target: CLCN2 (Chloride Channel 2 (CLCN2))

Andere Bezeichnung: CLCN2 (CLCN2 Produkte)

Synonyme: CLCN2 antikoerper, CLC2 antikoerper, LOC100150892 antikoerper, AL118368 antikoerper, ClC-2 antikoerper, Clc2 antikoerper, nmf240 antikoerper, CLC-2 antikoerper, CIC-2 antikoerper, ECA2 antikoerper, ECA3 antikoerper, EGI11 antikoerper, EGI3 antikoerper, EGMA antikoerper, EJM6 antikoerper, EJM8 antikoerper, clC-2 antikoerper, chloride voltage-gated channel 2 antikoerper, chloride channel, voltage-sensitive 2a antikoerper, chloride channel protein 2 antikoerper, chloride channel, voltage-sensitive 2 antikoerper, CLCN2 antikoerper, clcn2a antikoerper, EHI_142170 antikoerper, EHI_186860 antikoerper, Clcn2 antikoerper

Hintergrund: CLCN2 is a voltage-gated chloride channel, a class of proteins that have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. This protein is ubiquitously expressed, with moderate expression in aortic and coronary vascular smooth muscle cells and low levels expressed in aortic endothelial cells. Defects in CLCN2 may be the cause of epilepsy with grand mal seizures on awakening, childhood absence epilepsy type 3, and juvenile absence epilepsy. Single nucleotide polymorphisms (SNPs) of CLCN2 may also at as potential modifiers of cystic fibrosis disease severity.Synonyms: CIC-2, CIC2, CLC3, Chloride channel protein 2

Gen-ID: 1181

NCBI Accession: NP_001164558

UniProt: P51788