TRIM21 Antikörper (C-Term)

Produktnummer ABIN569661

Produktdetails anti-TRIM21 Antikörper

Target: TRIM21 (Tripartite Motif Containing 21 (TRIM21))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser TRIM21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequenz: CPLNIGSQGS TDY

Spezifität: Recognizes 52 Kd Ro Protein (TRIM21).

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Synthetic peptide (CPLNIGSQGSTDY) from C-terminus of Human TRIM21

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu TRIM21

Target: TRIM21 (Tripartite Motif Containing 21 (TRIM21))

Andere Bezeichnung: SS-A / Ro52 / TRIM21 (TRIM21 Produkte)

Synonyme: RNF81 antikoerper, RO52 antikoerper, SSA antikoerper, SSA1 antikoerper, Ro52 antikoerper, Ssa1 antikoerper, tripartite motif containing 21 antikoerper, tripartite motif-containing 21 antikoerper, TRIM21 antikoerper, Trim21 antikoerper

Hintergrund: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is part of the RoSSA ribonucleoprotein which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. The function of the RoSSA particle has not been determined. Two alternatively spliced transcript variants for this gene have been described, however, the full length nature of one variant has not been determined.Synonyms: E3 ubiquitin-protein ligase TRIM21, RING finger protein 81, RNF81, Ro(SS-A), SSA1, Sjoegren syndrome type A antigen, TRIM21, Tripartite motif-containing protein 21

Gen-ID: 6737

NCBI Accession: NP_003132

UniProt: P19474