BNIP1 Antikörper (Internal Region, Isoform 1)

Produktnummer ABIN375177

Produktdetails anti-BNIP1 Antikörper

Target: BNIP1 (BCL2/adenovirus E1B 19kDa Interacting Protein 1 (BNIP1))

Bindungsspezifität: Internal Region, Isoform 1

Reaktivität: Human, Maus, Ratte

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser BNIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to BNIP1. All reported variants represent isoform 1.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence C-DLLRQRKTTKESLAQ, from the internal region of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/8000. Western Blot: 0.5 - 1.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu BNIP1

Target: BNIP1 (BCL2/adenovirus E1B 19kDa Interacting Protein 1 (BNIP1))

Andere Bezeichnung: BNIP1 (BNIP1 Produkte)

Synonyme: NIP1 antikoerper, SEC20 antikoerper, TRG-8 antikoerper, 2010005M06Rik antikoerper, 5930429G21Rik antikoerper, Sec20 antikoerper, bnip1 antikoerper, BCL2 interacting protein 1 antikoerper, BCL2/adenovirus E1B interacting protein 1 antikoerper, BCL2/adenovirus E1B 19kDa interacting protein 1 S homeolog antikoerper, BNIP1 antikoerper, Bnip1 antikoerper, bnip1.S antikoerper

Hintergrund: BNIPs belong to the proapoptotic BH3-only protein family. Three isoforms have been described so far. BNIP 1 is involved in the maintenance of ER-integrity. It is a member of the syntaxin 18 complex which is involved in membrane trafficking between the ER and Golgi. Four different BNIP 1 splice variants have been described so far, one of which contains a highly conserved BH3 domain. All BNIP 1 variants are able to interact with the apoptosis regulators BCL2 and BCL2L1.Synonyms: BCL2/adenovirus E1B 19 kDa protein-interacting protein 1, NIP1, SEC20L, TRG8, Transformation-related gene 8 protein, Vesicle transport protein SEC20

Gen-ID: 662

NCBI Accession: NP_001196

UniProt: Q12981