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SULF2 Antikörper (Internal Region)

SULF2 Reaktivität: Human WB Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN375090
  • Target Alle SULF2 Antikörper anzeigen
    SULF2 (Sulfatase 2 (SULF2))
    Bindungsspezifität
    • 15
    • 9
    • 8
    • 7
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 41
    • 19
    • 19
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 54
    • 3
    • 1
    Ziege
    Klonalität
    • 55
    • 3
    Polyklonal
    Konjugat
    • 18
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SULF2 Antikörper ist unkonjugiert
    Applikation
    • 45
    • 25
    • 13
    • 13
    • 11
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Spezifität
    This antibody is expected to recognize both reported isoforms (NP_061325.1 and NP_940998.1).
    Aufreinigung
    Affinity Chromatography
    Immunogen
    Peptide with sequence C-DGRVYHVGLGDAAQPR, from the internal region of the protein sequence
    Top Product
    Discover our top product SULF2 Primärantikörper
  • Applikationshinweise
    Peptide ELISA: 1/8000. Western Blot: 0.3 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Tris saline, pH ~7.3 containing 0.02 % Sodium Azide and 0.5 % BSA
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    SULF2 (Sulfatase 2 (SULF2))
    Andere Bezeichnung
    SULF2 (SULF2 Produkte)
    Synonyme
    Sulf1 antikoerper, zgc:55612 antikoerper, SULF2 antikoerper, si:dkeyp-84g9.1 antikoerper, wu:fb48e04 antikoerper, HSULF-2 antikoerper, xtsulf2 antikoerper, 2010004N24Rik antikoerper, AU020235 antikoerper, MSulf-2 antikoerper, mKIAA1247 antikoerper, sulfatase 2a antikoerper, sulfatase 2 antikoerper, extracellular sulfatase Sulf-2 antikoerper, sulfatase 2b antikoerper, sulfatase 2 S homeolog antikoerper, sulf2a antikoerper, SULF2 antikoerper, LOC100540921 antikoerper, sulf2 antikoerper, sulf2b antikoerper, sulf2.S antikoerper, Sulf2 antikoerper
    Hintergrund
    Sulf-2 exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin. Mammalian Sulfs are endoproteolytically processed and secreted into the extracellular space of transfected cells, where they exhibit both arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity against intact heparin. Though the molecular weight of full length human Sulf2 is 100455 Da (870 amino acids), the endogenous Sulf2 is found by western blot to be present at molecular weights of 24.4, 33.7 and 51-60 kDa. Higher molecular weight species may be found depending on tissue and/or cell type. Analysis of human tumor tissue and tumor cell lines suggests that HSulf-1 is misregulated in cancers. HSulf-1 is found in a variety of normal tissues but is down-regulated in tumor cell lines originating from ovarian, breast, pancreatic, renal, and hepatocellular carcinoma. Tumors formed by cells expressing Sulf demonstrate enhanced extracellular matrix deposition. The 6-O-sulfation of heparan sulfate of myeloma tumor cells may be a critical factor in determiningand regulating the in vivo growth of this cancer.Synonyms: Extracellular sulfatase Sulf-2, KIAA1247
    Gen-ID
    55959, 9606
    UniProt
    Q8IWU5
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