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ERP29 Antikörper (C-Term)

ERP29 Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Schwein WB Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN375036
  • Target Alle ERP29 Antikörper anzeigen
    ERP29 (Endoplasmic Reticulum Protein 29 (ERP29))
    Bindungsspezifität
    • 15
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 49
    • 47
    • 33
    • 16
    • 13
    • 13
    • 12
    • 4
    • 2
    • 1
    • 1
    • 1
    Human, Ratte, Maus, Hund, Rind (Kuh), Schwein
    Wirt
    • 60
    • 4
    • 1
    Ziege
    Klonalität
    • 52
    • 11
    Polyklonal
    Konjugat
    • 23
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ERP29 Antikörper ist unkonjugiert
    Applikation
    • 41
    • 19
    • 14
    • 14
    • 14
    • 10
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Spezifität
    This antibody reacts to ERP29.
    Kreuzreaktivität (Details)
    Species reactivity (expected):Mouse, Rat, Canine, Bovine, Porcine.
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity chromatography
    Immunogen
    Peptide with sequence C-EKNKMSDGKKEELQ, from the C-Terminus of the protein sequence
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  • Applikationshinweise
    Peptide ELISA: 1/2000. Western Blot: 0.1 - 0.3 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0,5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    ERP29 (Endoplasmic Reticulum Protein 29 (ERP29))
    Andere Bezeichnung
    ERP29 (ERP29 Produkte)
    Synonyme
    C12orf8 antikoerper, ERp28 antikoerper, ERp31 antikoerper, PDI-DB antikoerper, PDIA9 antikoerper, 1200015M03Rik antikoerper, 2810446M09Rik antikoerper, AW209030 antikoerper, Erp28 antikoerper, Erp31 antikoerper, PDI-Db antikoerper, endoplasmic reticulum protein 29 antikoerper, ERP29 antikoerper, Erp29 antikoerper
    Hintergrund
    Proper protein folding and post-translational modifications are essential for secretory protein export out of the endoplasmic reticulum. This task is accomplished by chaperone proteins such as protein disulfide isomerase (PDI), GRP94, and BiP. A recently characterized protein, designated ERp29, is closely related to these chaperone proteins and appears to be upregulated during ER stress conditions. ERp29 is a soluble 259-residue protein that is localized to the lumen of the endoplasmic reticulum in all mammalian cells. Research has shown that there are two primary domains within ERp29. The first is the C-terminal region that is a novel, all helical, fold that is most likely involved with ERp29 retention to the ER. The second is the N-terminal region that resembles that of PDI's thioredoxin module. The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER.Synonyms: C12orf8, ERp28, ERp31, Endoplasmic reticulum protein ERp29
    Gen-ID
    10961
    NCBI Accession
    NP_006808
    UniProt
    P30040
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