UCP2 Antikörper (Internal Region)

Produktnummer ABIN374813

Produktdetails anti-UCP2 Antikörper

Target: UCP2 (Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser UCP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Sequenz: C-DSVKQFYTKG SEH

Spezifität: This antibody recognizes Uncoupling protein 2 / UCP2. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse, Rat, Canine (Dog).

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Synthetic peptide from from the internal region of Human UCP2 (NP_003346.2). Genename: UCP2

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/4000. Western Blot: 0.2 - 1 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Tris buffered saline, pH~7.3 0.02% Sodium Azide 0.5% BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.

Haltbarkeit: 12 months

Referenzen für anti-UCP2 Antikörper (ABIN374813)

Liu, Shim, Nguyen, Gibbons, Mitchell, Poirier: "Tempol protects cardiomyocytes from nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 139, Issue 1, pp. 133-41, (2014) (PubMed).

Details zu UCP2

Target: UCP2 (Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))

Andere Bezeichnung: SLC25A8 / UCP2 (UCP2 Produkte)

Synonyme: UCP2 antikoerper, DKFZp470P1633 antikoerper, ucp2 antikoerper, MGC53319 antikoerper, MGC75881 antikoerper, cb74 antikoerper, ATUCP2 antikoerper, K19M22.21 antikoerper, K19M22_21 antikoerper, uncoupling protein 2 antikoerper, BMIQ4 antikoerper, SLC25A8 antikoerper, UCPH antikoerper, Slc25a8 antikoerper, mitochondrial uncoupling protein 2 antikoerper, uncoupling protein 2 antikoerper, uncoupling protein 2 (mitochondrial, proton carrier) L homeolog antikoerper, uncoupling protein 2 (mitochondrial, proton carrier) antikoerper, uncoupling protein 1 antikoerper, PTRG_09289 antikoerper, UCP2 antikoerper, LOC100282746 antikoerper, ucp2.L antikoerper, ucp2 antikoerper, ucp1 antikoerper, Ucp2 antikoerper

Hintergrund: UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. UCP2 gene is expressed in many tissues, with the greatest expression in skeletal muscle. UCP2 is thought to play a role in non shivering thermogenesis, obesity and diabetes.
Alternate names: Mitochondrial uncoupling protein 2, Solute carrier family 25 member 8, UCP 2, UCP-2, UCPH

Gen-ID: 7351, 9606

UniProt: P55851

Pathways: Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Proton Transport