EFHD2 Antikörper (C-Term)

Produktnummer ABIN374490

Produktdetails anti-EFHD2 Antikörper

Target: EFHD2 (EF-Hand Domain Family, Member D2 (EFHD2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser EFHD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This anitbody reacts to EFHD2.

Kreuzreaktivität (Details): Species reactivity (expected):Rat, Canine, Bovine.
Species reactivity (tested):Human, Mouse.

Aufreinigung: Affinity chromatography

Immunogen: Peptide with sequence CAAFKELQSTFK, from the C Terminus of the protein sequence

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/16000. Western blot: 0.1 - 0.3 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-EFHD2 Antikörper (ABIN374490)

Brachs, Lang, Buslei, Purohit, Fürnrohr, Kalbacher, Jäck, Mielenz: "Monoclonal antibodies to discriminate the EF hand containing calcium binding adaptor proteins EFhd1 and EFhd2." in: Monoclonal antibodies in immunodiagnosis and immunotherapy, Vol. 32, Issue 4, pp. 237-45, (2013) (PubMed).

Chen, Li, Meng, Fan, Song, Wang, Zhu, Guo, Zhang, Shi: "Upregulation of B7-H1 expression is associated with macrophage infiltration in hepatocellular carcinomas." in: Cancer immunology, immunotherapy : CII, Vol. 61, Issue 1, pp. 101-8, (2012) (PubMed).

Napolitano, Pasqualetti, Usiello, Santini, Pacini, Sciamanna, Errico, Tassone, Di Dato, Martella, Cuomo, Fisone, Bernardi, Mandolesi, Mercuri, Standaert, Pisani: "Dopamine D2 receptor dysfunction is rescued by adenosine A2A receptor antagonism in a model of DYT1 dystonia." in: Neurobiology of disease, Vol. 38, Issue 3, pp. 434-45, (2010) (PubMed).

Wang, Paramasivam, Thomas, Bai, Kaminen-Ahola, Kere, Voskuil, Rosen, Galaburda, Loturco: "DYX1C1 functions in neuronal migration in developing neocortex." in: Neuroscience, Vol. 143, Issue 2, pp. 515-22, (2006) (PubMed).

Details zu EFHD2

Target: EFHD2 (EF-Hand Domain Family, Member D2 (EFHD2))

Andere Bezeichnung: EFHD2 (EFHD2 Produkte)

Synonyme: SWS1 antikoerper, efhd2 antikoerper, EFHD2 antikoerper, MGC131292 antikoerper, 2600015J22Rik antikoerper, AA408606 antikoerper, D4Wsu27e antikoerper, si:dkey-72l14.9 antikoerper, wu:fb80e07 antikoerper, EF-hand domain family member D2 antikoerper, EF-hand domain family, member D2 antikoerper, EF-hand domain family member D2 L homeolog antikoerper, EF hand domain containing 2 antikoerper, EFHD2 antikoerper, Efhd2 antikoerper, efhd2 antikoerper, efhd2.L antikoerper

Hintergrund: EFDH2 is a protein whose gene expression is increased in purified populations of CD8 lymphocytes, when compared to CD19 and CD4 lymphocytes. EFDH2 contains two potential EF-hand domains, and therefore may have a role in calcium signaling. Its predominant presence in CD8 lymphocytes suggests that it may be involved in functions that are important for cytotoxic lymphocytes.Synonyms: EF-hand domain-containing protein D2, SWS1, Swiprosin 1, Swiprosin-1

Gen-ID: 79180

NCBI Accession: NP_077305

UniProt: Q96C19