ATP6AP2 Antikörper (C-Term)

Produktnummer ABIN374363

Produktdetails anti-ATP6AP2 Antikörper

Target: ATP6AP2 (ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh)

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser ATP6AP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequenz: C-SIIYRMTNQK IRMD

Spezifität: This antibody detects Renin Receptor at C-term.

Kreuzreaktivität (Details): Species reactivity (expected):Cow.
Species reactivity (tested):Human, Mouse, Rat.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide from C Terminus of the protein sequence according to NP_005756.2 Genename: ATP6AP2

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit dilution 1: 16000. Western blot: 0.25-1 μg/mL. Approx 37 kDa band observed in Human Kidney lysates(predicted size of approx.40Kda according to NP_005756).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-ATP6AP2 Antikörper (ABIN374363)

Happold, Roth, Wick, Schmidt, Florea, Silginer, Reifenberger, Weller: "Distinct molecular mechanisms of acquired resistance to temozolomide in glioblastoma cells." in: Journal of neurochemistry, Vol. 122, Issue 2, pp. 444-55, (2013) (PubMed).

Zhu, Yoneda, Demura, Karashima, Usukura, Yamagishi, Takeda: "Effect of mineralocorticoid receptor blockade on the renal renin-angiotensin system in Dahl salt-sensitive hypertensive rats." in: Journal of hypertension, Vol. 27, Issue 4, pp. 800-5, (2009) (PubMed).

Details zu ATP6AP2

Target: ATP6AP2 (ATPase, H+ Transporting, Lysosomal Accessory Protein 2 (ATP6AP2))

Andere Bezeichnung: Renin Receptor (ATP6AP2 Produkte)

Synonyme: APT6M8-9 antikoerper, ATP6IP2 antikoerper, ATP6M8-9 antikoerper, ELDF10 antikoerper, M8-9 antikoerper, MRXE antikoerper, MSTP009 antikoerper, XMRE antikoerper, (P)RR antikoerper, 5730403E06Rik antikoerper, Atp6ip2 antikoerper, tj6 antikoerper, wss antikoerper, arcl antikoerper, j6b7 antikoerper, stv1 antikoerper, tj6m antikoerper, tj6s antikoerper, vph1 antikoerper, atp6a2 antikoerper, atp6n1d antikoerper, ATP6AP2 antikoerper, DKFZp459G0918 antikoerper, atp6ap2 antikoerper, wu:fj36c03 antikoerper, wu:fq15e04 antikoerper, zgc:73194 antikoerper, ATPase H+ transporting accessory protein 2 antikoerper, ATPase, H+ transporting, lysosomal accessory protein 2 antikoerper, ATPase H+ transporting V0 subunit d2 antikoerper, ATPase H+ transporting V0 subunit a2 antikoerper, ATPase, H+ transporting, lysosomal accessory protein 2 S homeolog antikoerper, ATP6AP2 antikoerper, Atp6ap2 antikoerper, ATP6V0D2 antikoerper, atp6v0a2 antikoerper, atp6ap2.S antikoerper, atp6ap2 antikoerper

Hintergrund: Synonyms: ATP6AP2, ATP6IP2, ATP6M8-9, ATPase H(+)-transporting lysosomal accessory protein 2, ATPase H(+)-transporting lysosomal-interacting protein 2, CAPER, ELDF10, ER-localized type I transmembrane adaptor, Embryonic liver differentiation factor 10, HT028, MSTP009, N14F, PSEC0072, Renin/prorenin receptor, Vacuolar ATP synthase membrane sector-associated protein M8-9

Gen-ID: 10159

NCBI Accession: NP_005756

UniProt: O75787

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones